Adenine and blood storage

BAL Hurn, DN Wahitmore, SP Lock - Vox Sanguinis, 1966 - Wiley Online Library
blood containing adenine have now been given and no toxic effects have occurred. The actual
mechanism of the loss of viability of stored red blood cells … the metabolism of glucose. But …

Red blood cell aging markers during storage in citrate‐phosphate‐dextrose–saline‐adenineglucose‐mannitol

MH Antonelou, AG Kriebardis, KE Stamoulis… - …, 2010 - Wiley Online Library
… storage of RBCs in citrate-phosphate-dextrose-adenine (CPDA) plasma. Here we report a
similar analysis of RBCs stored in saline-adenine-glucose-mannitol (SAGM). In addition, we …

Evaluation of canine red blood cells stored in a saline, adenine, and glucose solution for 35 days

KJ Wardrop, RL Tucker… - Journal of Veterinary …, 1997 - Wiley Online Library
… for stored human whole blood or red blood cells state that at … blood banks, saline, glucose,
and adenine solutions, also known as additive solutions, are added directly to red blood cells, …

In vitro measures of membrane changes reveal differences between red blood cells stored in saline‐adenineglucose‐mannitol and AS‐1 additive solutions: a paired …

RL Sparrow, A Sran, G Healey, MF Veale… - Transfusion, 2014 - Wiley Online Library
… Many European blood centers use saline-adenine-glucose-mannitol (SAGM) AS, whereas
… SAG formulation by increasing the concentrations of adenine, glucose, and mannitol (Table 1…

… of prestorage leukoreduction and subsequent irradiation on in vitro red blood cell (RBC) storage variables of RBCs in additive solution saline‐adenineglucose …

R Zimmermann, S Wintzheimer, V Weisbach… - …, 2009 - Wiley Online Library
… effect of irradiation on glucose levels, hemolysis, and MCV … blood and 40 RBC units
that were filtered after component separation. All RBCs were stored in the AS saline-adenine-glucose

Improved red blood cell storage using optional additive systems (OAS) containing adenine, glucose and ascorbate‐2‐phosphate

GL Moore, ME Ledford, MR Brummell - Transfusion, 1981 - Wiley Online Library
… (the SAG and the optional additive system (OAS) using adenine, glucose, plus additional …
we evaluate extended red blood cell storage (to 42 days) with maintenance of red blood cell 2,3…

Metabolic fate of adenine in red blood cells during storage in SAGM solution

G Paglia, ÓE Sigurjónsson, A Bordbar, Ó Rolfsson… - …, 2016 - Wiley Online Library
… (RBCs) is an integral part of modern healthcare and relies on blood banking technologies …
saline solution containing glucose, adenine, and mannitol.4, 5 Both glucose and adenine are …

… red blood cell susceptibility to in vitro transfusion‐associated stress conditions is higher after longer storage and increased by storage in saline‐adenineglucose …

D Mittag, A Sran, KS Chan, MP Boland… - …, 2015 - Wiley Online Library
… Leukoreduced whole blood donations (n = 18) were paired, mixed, and resplit before
separating the RBCs for storage in saline‐adenineglucose‐mannitol (SAGM) or AS‐1. Samples …

Cellular properties of human erythrocytes preserved in saline–adenineglucose–mannitol in the presence of L‐carnitine

A Arduini, G Minetti, A Ciana, C Seppi… - American journal of …, 2007 - Wiley Online Library
… L-Carnitine (LC) in the preservation medium during storage of red blood cells (… cell-age
related responses to storage conditions and to LC. RBC concentrates in saline-adenine-glucose-…

Platelet glycolysis in platelet storage IV. The effect of supplemental glucose and adenine

E Beutler, W Kuhl - Transfusion, 1980 - Wiley Online Library
… The role of adenine in serving as substrate for ATP synthesis in the red blood cell and in
improving viability of stored red blood cells is now well known? An increase in glucose