Adenylate cyclase activity in human pancreatic adenocarcinoma cell lines

L Al-Nakkash, NL Simmons, JM Lingard… - International journal of …, 1996 - Springer
pancreatic disease, we wished to establish which duct cells receptors are functional on
adenocarcinoma cell … cyclase activity in six human pancreatic adenocarcinoma cell lines. Known …

Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas

JMD Plate, AE Plate, S Shott, S Bograd… - Cancer Immunology …, 2005 - Springer
… an augmentation of immune T-cell functions that resulted in antitumor activity [5]. Our … of
T-cell activity in pancreas of cancer patients treated with gemcitabine. T-cell activity is regulated …

Decreased natural killer cell activity and interferon production by leucocytes in patients with adenocarcinoma of the pancreas.

K Funa, B Nilsson, G Jacobsson, GV Alm - British journal of cancer, 1984 - ncbi.nlm.nih.gov
… The present study shows that patients with pancreatic adenocarcinoma have both a decreased
basal NK activity and a decreased in vitro reponse of NK cells to IFN-a. There are several …

A cystic fibrosis pancreatic adenocarcinoma cell line.

RA Schoumacher, J Ram… - Proceedings of the …, 1990 - National Acad Sciences
… a pancreatic adenocarcinoma cell line (CFPAC-1) from a patient with cystic fibrosis (CF) and
assessed some of its properties. The cellsactivity was elicited by 5 ,uM cAMP in both cell

ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma

MP Kim, JB Fleming, H Wang, JL Abbruzzese, W Choi… - PloS one, 2011 - journals.plos.org
pancreatic cancer cells injected into NOD/SCID mice, we demonstrate that cell populations
enriched for high ALDH activity … original tumor independent of CD133 cell surface expression. …

Genetics and biology of pancreatic ductal adenocarcinoma

AF Hezel, AC Kimmelman, BZ Stanger… - Genes & …, 2006 - genesdev.cshlp.org
Pancreatic precursor lesions and genetic events involved in pancreatic adenocarcinoma
carcinogenesis by additional mechanisms distinct from its regulation of G1 CDK activity. …

Genetics and biology of pancreatic ductal adenocarcinoma

H Ying, P Dey, W Yao, AC Kimmelman… - Genes & …, 2016 - genesdev.cshlp.org
… metabolic syndrome, pancreatic ductal adenocarcinoma (PDAC) is … of cancer cell biology,
particularly altered cancer cell … that show strong preclinical activity. Elucidation of tumor biology …

[HTML][HTML] Targeting cancer cell metabolism in pancreatic adenocarcinoma

R Cohen, C Neuzillet, A Tijeras-Raballand, S Faivre… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… In tumors with intact p53, autophagy inhibition resulted in decreased metabolism activity, …
glucose consumption for anabolic pathway activity, fueling cancer cell proliferation. PDAC …

Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity

P Loukopoulos, K Kanetaka, M Takamura, T Shibata… - Pancreas, 2004 - journals.lww.com
… In the present study, a series of orthotopic models of human pancreatic adenocarcinoma
was successfully established in SCID mice, derived from both pancreatic cancer cell lines and …

The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance

M Erkan, C Reiser-Erkan, CW Michalski… - Current molecular …, 2012 - ingentaconnect.com
… Clinically, stromal activity of the pancreatic ductal adenocarcinoma has as great an impact
on patient prognosis as the lymph node status of the tumor. The exact molecular mechanisms …