Adenosine A2A and A2B receptors are both required for adenosine A1 receptor-mediated cardioprotection

E Zhan, VJ McIntosh, RD Lasley - American Journal of …, 2011 - journals.physiology.org
… more than one receptor subtype. The purpose of this study was to determine whether adenosine
A 2A and/or A 2B receptors modulate adenosine A 1 receptor-mediated cardioprotection…

Potent antagonists for the human adenosine A2B receptor. Derivatives of the triazolotriazine adenosine receptor antagonist ZM241385 with high affinity

M De Zwart, RC Vollinga, MW Beukers… - Drug development …, 1999 - Wiley Online Library
… showed a high A2B receptor affinity (Ki = 7.6 nM), while it was equally active at A2A
receptors, being A2B receptor-selective with respect to A1 and A3 receptors. Drug Dev. Res. …

Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma.

I Feoktistov, I Biaggioni - The Journal of clinical …, 1995 - Am Soc Clin Investig
adenosine plays a role in asthma. We believe it is important to determine the adenosine
receptorAdenosine A2 receptors have been reputed to potentiate activation of partially purified …

Role of adenosine A2b receptor overexpression in tumor progression

C Sepúlveda, I Palomo, E Fuentes - Life sciences, 2016 - Elsevier
… Thus A2b participates in different events, such as angiogenesis … Therefore, adenosine A2b
receptor appears as an … of adenosine A2b receptor in tumor angiogenesis and metastasis. …

Effects of Adenosine A2A and A2B Receptor Activation on Signaling Pathways and Cytokine Production in Human Uroepithelial Cells

S Säve, K Persson - Pharmacology, 2010 - karger.com
… between adenosine A2a and A2b receptor signaling in … found for the adenosine A2b receptor,
while adenosine A2a receptor … characteristics of adenosine A 2 receptors involve inhibition …

Distribution of adenosine A1, A2A and A2B receptors in human skeletal muscle

Lynge, Hellsten - Acta Physiologica Scandinavica, 2000 - Wiley Online Library
… the adenosine A1, A2A and A2B receptors in transverse sections of human skeletal muscle.
(a) Positive fluorescent staining with an adenosine A2A receptor … an adenosine A2B receptor

Pharmacology of adenosine A2A receptors and therapeutic applications

BB Fredholm, RA Cunha… - Current topics in …, 2003 - ingentaconnect.com
… do not express adenosine A2A receptor mRNA and there is no expression of A2A receptors
in … Both A2A and A2B receptors stimulate the formation of cAMP, but other actions, including …

Ligand-Specific Binding and Activation of the Human Adenosine A2B Receptor

D Thimm, AC Schiedel, FF Sherbiny, S Hinz… - Biochemistry, 2013 - ACS Publications
… analogues, nonselective, and even less potent at A 2B receptors than at the other
adenosine receptor subtypes. 1-Deoxy-1-[6-[N′-(furan-2-carbonyl)hydrazino]-9H-purin-9-yl]-N-ethyl-β…

A2b adenosine receptors can change their spots

MV Cohen, X Yang, JM Downey - British journal of …, 2010 - Wiley Online Library
receptors have been characterized pharmacologically and have been cloned, our familiarity
and appreciation of the A 2b adenosine receptoradenosine receptors may not be accurate. …

[HTML][HTML] Adenosine A2A receptor is involved in cell surface expression of A2B receptor

K Moriyama, MV Sitkovsky - Journal of Biological Chemistry, 2010 - ASBMB
The A2A and A2B adenosine receptors (A2AR and A2BR) are implicated in many physiological
processes. However, the mechanisms of their intracellular maturation and trafficking are …