The role of adenosine A2A and A2B receptors in the regulation of TNF-α production by human monocytes

JG Zhang, L Hepburn, G Cruz, RA Borman… - Biochemical …, 2005 - Elsevier
… The lack of such information impacts on the selection of adenosine receptor agonists for …
adenosine receptor agonist, 5′-N-ethylcarboxamidoadenosine (NECA) or the A 2A receptor

Adenosine A2A receptor ligands: Effects on neuronal excitability

JW Phillis - Drug development research, 2001 - Wiley Online Library
… in the cloning of two receptors, the high-affinity A2A and lower-affinity A2Badenosine A1
receptors following A2A receptor activation and the antagonistic effects of A2A receptors on …

Adenosine A2Breceptor‐mediated cyclic AMP accumulation in primary rat astrocytes

MC Peakman, SJ Hill - British journal of pharmacology, 1994 - Wiley Online Library
A2B-adenosine receptor coupled positively to adenylyl cyclase. Furthermore, the presence
of Al-receptors … no significant effect on the A2B-receptor-mediated cyclic AMP responses to …

A2A and A2B adenosine receptors: The extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine

E De Filippo, S Hinz, V Pellizzari, G Deganutti… - Biochemical …, 2020 - Elsevier
… A 2A and A 2B adenosine receptors (ARs) are closely related G protein-coupled receptor
Despite their almost identical binding sites for adenosine, A 2A ARs are activated by low (…

Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation

MG Feng, LG Navar - American Journal of Physiology …, 2010 - journals.physiology.org
… and superfused with solutions containing adenosine or adenosine A 2 receptor agonist (CV-1808)
along with adenosine A 2B and A 2A receptor blockers. Adenosine (10 μmol/l) …

Adenosine inhibits tumor necrosis factor-α release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor

LM Kreckler, TC Wan, ZD Ge, JA Auchampach - Journal of Pharmacology …, 2006 - ASPET
… of adenosine have been attributed to signaling through the A 2A adenosine receptor (A
2A … Previously, however, it has been shown that the A 3 AR agonist N 6 -(3-iodobenzyl)adenosine

Therapeutic potential of agonists and antagonists of A1, A2a, A2b and A3 adenosine receptors

S Jamwal, A Mittal, P Kumar… - Current …, 2019 - ingentaconnect.com
… On the basis of adenosine’s binding affinity, these A2 receptors are subdivided into … as A2A
receptors having the higher affinity and A2B receptors having the lower affinity for adenosine […

Adenosine A2A and A2B receptors are both required for adenosine A1 receptor-mediated cardioprotection

E Zhan, VJ McIntosh, RD Lasley - American Journal of …, 2011 - journals.physiology.org
… more than one receptor subtype. The purpose of this study was to determine whether adenosine
A 2A and/or A 2B receptors modulate adenosine A 1 receptor-mediated cardioprotection…

Differential Expression of Adenosine Receptors in Human Endothelial Cells: Role of A2B Receptors in Angiogenic Factor Regulation

I Feoktistov, AE Goldstein, S Ryzhov, D Zeng… - Circulation …, 2002 - Am Heart Assoc
… To test the hypothesis that differential expression of adenosine receptor subtypes contributes
… A 2A adenosine receptors and HMEC-1 preferentially express A 2B receptors. Neither cells …

Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis

JS Frick, CF MacManus, M Scully… - The Journal of …, 2009 - journals.aai.org
… we hypothesized that specific Ado receptors would contribute to … express predominantly the
Ado A2B receptor (AA2BR) and to … . The adenosine A2A receptor agonist CGS 21680 fails to …