… findings demonstrated the importance of adenosine receptor (AR) signaling for … human
brain endothelial cells possess the capacity to generate and respond to extracellular adenosine. …

… to outline evidence that adenosine receptor (AR) activation can modulate blood–brain barrier
(… that human brain endothelial cells do respond to adenosine in vitro, agonist-induced A 2A …

… adenosine receptor subtype in retinal endothelial cells. Furthermore, distinct adenosine
receptor subtypes may mediate the proliferative effects of adenosine in endothelial cells from …

… Selective AR activation resulted in cellular changes in vitro including decreased transendothelial
… AR signaling at brain endothelial cells represents a novel endogenous mechanism of …

… entry of cells and molecules into the CNS. Because extracellular adenosine mediates many
of … that signaling via adenosine receptors on BBB endothelial cells signals the recruitment of …

… We report differential expression of adenosine receptor subtypes in endothelial cells of
disparate origin; A 2A receptors are the predominant subtype in HUVECs and A 2B …

… by activating A 2A adenosine receptor (AR), … brain capillary endothelial cells. However, due
to transient circulation lifetime of adenosine-based agonists, their capability to enhance brain …

… and adenosine receptor activation following modest increases in extracellular adenosine
concentrations have … microvascular endothelial cells and its upregulation by adenosine. …

… endothelium that may contain 10 12 –10 13 endothelial cells (… represent critical sites of
adenosine receptor action upon the … In this review, we will describe specific aspects of endothelial …

… of adenosine as a breakdown product, acting at the G i -coupled adenosine receptors on
the cells, … of response to adenosine (up to 100 μM) or other adenosine receptor subtype-specific …