… ) of anchorage-dependent cells, such as endothelial cells. Basal FAK activity in non-stimulated
endothelial cells is important in maintaining cell adhesion to integrins via PI3 kinase/Akt …

… modulate cell migration (13, 14). Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase
that … Phosphorylation of FAK at Tyr-397 [p-FAK(Y397)] upon cell adhesion allows FAK to …

… (FAs) are complex structures assembled at the abluminal endothelial … In this review we
focus on focal adhesion kinase (FAK), a … on potential implications on endothelial cell functions. …

… -kinase activity. VEGF caused a marked increase in tyrosine phosphorylation of p125 focal
adhesion kinase (… VEGF produced similar effects on p125 FAK in the endothelial cell line ECV.…

… Pretreating cells with VEGF antibodies or with the specific inhibitor SU-1498, which inhibits
… stimulate focal adhesion assembly. VEGF induced the coupling of focal adhesion kinase (FAK…

… signal-regulated kinase (ERK), and tyrosine phosphorylation of focal adhesion kinase (p125FAK).
Therefore, we propose that AM induces angiogenesis in endothelial cells through the …

… Atherogenesis involves activation of NF-κB in endothelial cells by fluid shear stress. Because
this pathway involves integrins, we investigated the involvement of focal adhesion kinase (…

… adhesion kinase is implicated in the regulation of cell adhesion, migration, survival, and
cell-… However, the functions of focal adhesion kinase in endothelial cell (EC) in vivo remain …

… - to 130-kDa cellular proteins, which were determined by immunoprecipitation with specific
antibodies focal adhesion kinase (p125 FAK ) and paxillin (p68). Brief exposure of cells to a …

… process are membrane blebbing, loss of focal adhesion sites, and retraction from the matrix
… focal adhesion kinase (pp125 FAK ), an important component of the focal adhesion complex, …