Properties and functions of adipose tissue macrophages in obesity

L Russo, CN Lumeng - Immunology, 2018 - Wiley Online Library
… and signaling profiles in macrophages during obesity-induced AT inflammation are not fully
… what is known about adipose tissue macrophage (ATM) biology in the setting of obesity and …

Role of adipose tissue macrophages in obesity-related disorders

S Chakarov, C Blériot, F Ginhoux - Journal of Experimental Medicine, 2022 - rupress.org
… of the adipose tissue environment, while highlighting its heterogeneity. Finally, we detail
how obesity transforms both adipose tissue and local macrophage populations. Understanding …

[HTML][HTML] Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses

L Boutens, GJ Hooiveld, S Dhingra, RA Cramer… - Diabetologia, 2018 - Springer
adipose tissue macrophages (ATMs) in lean and obeseadipose tissue macrophages (ATMs)
has led to the identification of M2 macrophages in lean adipose tissue vs M1 macrophages

Adipose tissue macrophages: their role in adipose tissue remodeling

T Suganami, Y Ogawa - Journal of leukocyte biology, 2010 - academic.oup.com
… On the other hand, pioglitazone treatment improves the unbalanced M1/M2 phenotype of
adipose tissue macrophages in diet-induced obese mice [59]. Moreover, a recent study …

[HTML][HTML] Adipose tissue macrophages: going off track during obesity

L Boutens, R Stienstra - Diabetologia, 2016 - Springer
macrophages in lean and obese adipose tissue. The origin of macrophages residing in lean
and obese adipose tissue … ATMs during the development of obesity will be discussed. Finally…

Adipose tissue macrophages

M Zeyda, TM Stulnig - Immunology letters, 2007 - Elsevier
… and are capable of anti-inflammatory mediator production challenging the concept that
ATMs are simply the “bad guys” in obese adipose tissue. Triggers promoting ATM recruitment, …

[HTML][HTML] New insights into adipose tissue macrophages in obesity and insulin resistance

Z Cai, Y Huang, B He - Cells, 2022 - mdpi.com
… of adipose tissue macrophages (ATMs) beyond classical M1/M2 polarization in obesity and
… diverse subpopulations of ATMs in the context of obesity. Furthermore, we review the recent …

Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

CN Lumeng, JB DelProposto, DJ Westcott… - Diabetes, 2008 - Am Diabetes Assoc
… between ATMs in lean and obese mice is the accumulation of MGL1 − ATMs. To confirm
this, we analyzed the SVF from adipose tissue from lean and obese mice by flow cytometry. Of …

Adipose tissue macrophages as a therapeutic target in obesity‐associated diseases

AA Herrada, A Olate‐Briones, A Rojas, C Liu… - Obesity …, 2021 - Wiley Online Library
… 19 years of age) are overweight or obese, 1 an increase of nearly … evidence that AT-infiltrating
macrophages (ATMs) play a … discuss macrophage biology and pathophysiology in obesity-…

[HTML][HTML] Obesity induces a phenotypic switch in adipose tissue macrophage polarization

CN Lumeng, JL Bodzin, AR Saltiel - The Journal of clinical …, 2007 - Am Soc Clin Investig
Adipose tissue macrophages (ATMs) infiltrate adipose tissue during obesity and contribute
to insulin resistance. We hypothesized that macrophages migrating to adipose tissue upon …