A proposed modulatory role of the endocannabinoid system on adipose tissue metabolism and appetite in periparturient dairy cows

MN Myers, M Zachut, J Tam, GA Contreras - Journal of animal science and …, 2021 - Springer
To sustain the nutrient demands of rapid fetal growth, parturition, and milk synthesis,
periparturient dairy cows mobilize adipose tissue fatty acid stores through lipolysis. This process …

Regulatory B cell–specific interleukin-10 is dispensable for atherosclerosis development in mice

AP Sage, M Nus, LL Baker, AJ Finigan… - … , and vascular biology, 2015 - Am Heart Assoc
… In contrast to its prominent regulatory role in many immune-mediated diseases and its
proposed modulatory role in atherosclerosis, B cell–derived IL-10 does not alter atherosclerosis in …

Modulating immunometabolism in transition dairy cows: the role of inflammatory lipid mediators

M Zachut, J Tam, GA Contreras - Animal Frontiers, 2022 - academic.oup.com
… of immune and metabolic functions. Periparturient lipolysis in adipose tissues increases the
… were also evaluated in adipose tissues and liver; in adipose tissues, it was found that CLA …

Endocannabinoids produced by white adipose tissue modulate lipolysis in lean but not in obese rodent and human

C Buch, T Muller, J Leemput… - Frontiers in …, 2021 - frontiersin.org
… TG deposit and protect from the development of metabolic diseases (41). However, … adipose
tissue hypertrophy favoring adipocyte dysfunction and finally impact the whole metabolism (…

Overactivation of the endocannabinoid system alters the antilipolytic action of insulin in mouse adipose tissue

T Muller, L Demizieux… - … and Metabolism, 2017 - journals.physiology.org
metabolic risk. The main function of adipose tissue (AT) is to store excess energy as neutral
fat during periods of nutritional excess and to deliver substrates, free fatty acids (FFA) and …

[HTML][HTML] Cannabinoid-1 receptor activation modulates lipid mobilization and adipogenesis in the adipose tissue of dairy cows

MN Myers, U Abou-Rjeileh, M Chirivi… - Journal of Dairy …, 2023 - Elsevier
… Amplified adipose tissue (AT) lipolysis and suppressed lipogenesis characterize the …
Adipose tissue explants were collected from healthy, nonlactating and nongestating (NLNG; …

The paraventricular nucleus of the thalamus alters rhythms in core temperature and energy balance in a state-dependent manner

S Bhatnagar, MF Dallman - Brain research, 1999 - Elsevier
… with systems that regulate metabolism, including core temperature … were considered epididymal
white adipose tissue and white fats … This proposed modulatory role for the PVTh in core …

Effects of environmental heat load on endocannabinoid system components in adipose tissue of high yielding dairy cows

G Kra, JR Daddam, U Moallem, H Kamer, M Ahmad… - Animals, 2022 - mdpi.com
… We hypothesized that environmental heat load (HL) may affect the endocannabinoid
system (ECS), a central regulator of metabolism and the stress response, in adipose tissue (AT), …

Effects of omega-3 supplementation on components of the endocannabinoid system and metabolic and inflammatory responses in adipose and liver of peripartum …

G Kra, JR Daddam, U Moallem, H Kamer… - Journal of Animal …, 2022 - Springer
adipose tissue and liver are the main metabolic organs that participate in the adaptations of
dairy cows to onset of lactation; however, exceeded adipose tissue … and affect metabolic and …

Lipolysis pathways modulate endocannabinoid biosynthesis and signaling networks in dairy cows' adipocytes

MN Myers, M Chirivi, JC Gandy, J Tam, M Zachut… - 2024 - researchsquare.com
… : A proposed modulatory role of the endocannabinoid system on adipose tissue metabolism
… mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol …