Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non–small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial

K Kelly, NK Altorki, WEE Eberhardt… - Journal of Clinical …, 2015 - escholarship.org
… that erlotinib would be efficacious in the adjuvant setting. … Adjuvant erlotinib did not improve
DFS in patients with EGFR … patients might benefit from adjuvant erlotinib was based on data …

[HTML][HTML] SELECT: a phase II trial of adjuvant erlotinib in patients with resected epidermal growth factor receptor–mutant non–small-cell lung cancer

NA Pennell, JW Neal, JE Chaft, CG Azzoli… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
… In this open-label phase II trial, patients with resected stage IA to IIIA (7 th edition of the …
Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non-small-cell lung cancer (…

Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - The Lancet …, 2018 - thelancet.com
… therapy in patients with completely resected stage IBIIIA NSCLC. However, gefitinib did
not show superiority over placebo in terms of either disease-free or overall survival. One …

Erlotinib as adjuvant therapy in EGFR-mutant NSCLC

J Jassem - The Lancet Respiratory Medicine, 2018 - thelancet.com
… Moreover, the superiority of erlotinib over chemotherapy … erlotinib versus 20% with
chemotherapy. Recently, a phase 3 Chinese trial (ADJUVANT) that enrolled patients with stage …

[HTML][HTML] Erlotinib as standard adjuvant therapy for resectable EGFR mutation-positive non-small cell lung cancer

S Tanaka, J Uchino - Translational Lung Cancer Research, 2019 - ncbi.nlm.nih.gov
… ) as an adjuvant treatment for stage IB-IIIA NSCLC. The … gefitinib as adjuvant chemotherapy
for EGFR-positive stage IIIA-… adjuvant treatment after curative resection of stage IIIA NSCLC, …

Adjuvant erlotinib (E) versus placebo (P) for completely resected stage IB-IIIA EGFR-positive (IHC/FISH) non-small cell lung cancer (NSCLC): RADIANT Results …

NK Altorki, MER O'brien, WEE Eberhardt… - International Journal of …, 2014 - redjournal.org
… Pts with completely resected IB-IIIA NSCLC were randomized 2:1 to receive E 150 mg qd
or P for 2 years. Pts were stratified according to stage, histology, prior adjuvant chemotherapy, …

… Exploratory Analysis From Randomized, Phase II EVAN Study of Erlotinib Versus Vinorelbine Plus Cisplatin Adjuvant Therapy in Stage IIIA Epidermal Growth Factor …

D Yue, S Xu, Q Wang, X Li, Y Shen… - Journal of Clinical …, 2022 - ingentaconnect.com
… (23.4% v 23.7% with chemotherapy) trials,12 erlotinib … of adjuvant erlotinib for patients
with resected stage IA-IIIA EGFR1 … stages, especially those with stage IB, need to be clarified. …

Rational application of EGFR-TKI adjuvant therapy in patients with completely resected stage IB-IIIA EGFR-mutant NSCLC: a systematic review and meta-analysis of …

SL Zhang, XF Yi, LT Huang, L Sun, JT Ma, CB Han - BMC cancer, 2023 - Springer
… showed that adjuvant erlotinib improved both DFS and OS in patients with EGFR-mutant
stage IIIA NSCLC compared with chemotherapy [15]. Thus, whether adjuvant therapy with EGFR…

Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the …

WZ Zhong, HH Yan, KN Chen, C Chen… - Signal transduction and …, 2023 - nature.com
adjuvant setting, showed remarkable preliminary DFS improvement in patients with stage
IB-IIIA … for comparing erlotinib with GC as neoadjuvant/adjuvant therapy in patients with stage …

[HTML][HTML] Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations

YY Janjigian, BJ Park, MF Zakowski, M Ladanyi… - Journal of Thoracic …, 2011 - Elsevier
… in stage IIIA. … IIIA disease and approximately 4% for patients with stage IB NSCLC. For stage
IA disease, despite the unacceptably high recurrence rate at 5 years, treatment with adjuvant