Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents
MM Morcoss, MN El Shimaa, RA Ibrahem… - Bioorganic …, 2020 - Elsevier
… The study was expanded to forecast the mechanism of action … In silico ADME prediction
investigations also forecasting the … The outcomes of the predicted ADME parameters are shown …
investigations also forecasting the … The outcomes of the predicted ADME parameters are shown …
[HTML][HTML] In Silico ADME and toxicity prediction of benzimidazole derivatives and its cobalt coordination compounds. synthesis, characterization and crystal structure
A Raducka, M Świątkowski, K Gobis, P Szymański… - Molecules, 2022 - mdpi.com
… cobalt coordination compounds with non-commercial benzimidazole derivatives. Our work
is a … The choice fell on benzimidazole derivatives due to the wide spectrum of activity, and in …
is a … The choice fell on benzimidazole derivatives due to the wide spectrum of activity, and in …
Synthesis, ADMET, drug likeness and in silico activities of benzimidazole derivative
… structure of synthesized benzimidazole derivatives were drawn using … predictions were
done using DATA Warrior and Swiss ADME, the “molecular docking activity” of all the derivatives …
done using DATA Warrior and Swiss ADME, the “molecular docking activity” of all the derivatives …
Synthesis, molecular docking and ADME prediction of some new benzimidazole carboxamidines derivatives as antimicrobial agents
… In this study, 15 new 1H-benzimidazole-5-carboxamidine derivative compounds that could …
of the new benzimidazole derivatives were weaker than standard drugs, but some derivatives …
of the new benzimidazole derivatives were weaker than standard drugs, but some derivatives …
[PDF][PDF] QSAR, molecular docking and ADME studies of benzimidazole derivatives as antibacterial agents
V Kumar - European Chemical Bulletin, 2023 - researchgate.net
… , and ADME studies of benzimidazole derivatives against Escherichia … The antibacterial
activity of benzimidazole derivatives is … and ADME Studies for the prediction of Benzimidazole …
activity of benzimidazole derivatives is … and ADME Studies for the prediction of Benzimidazole …
[HTML][HTML] Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1, 2, 3-triazole-sulfonamide hybrids as antimicrobial and …
FF Al-Blewi, MA Almehmadi, MR Aouad… - Chemistry Central …, 2018 - Springer
… , benzimidazole and sulfonamides moieties in one scaffold via a Cu(I)-catalysed 1,3-dipolar
cycloaddition reaction of sulfa drug azides with propargylated benzimidazoles derivatives …
cycloaddition reaction of sulfa drug azides with propargylated benzimidazoles derivatives …
Synthesis, molecular modeling, quantum mechanical calculations and ADME estimation studies of benzimidazole-oxadiazole derivatives as potent antifungal agents
… benzimidazole derivatives can be CYP51 inhibitors [13], [14], [15], [16]. Furthermore, ADME
… In this study, we predict MM-PBSA through the different energy parameters such as Van der …
… In this study, we predict MM-PBSA through the different energy parameters such as Van der …
Design, synthesis and ADMET prediction of bis-benzimidazole as anticancer agent
M Rashid - Bioorganic chemistry, 2020 - Elsevier
… was also used to estimate ADME and toxicity of synthetic … bis-benzimidazole derivatives
and predict their physiochemical … explorer, Pre ADMET prediction and Lazar toxicity prediction. …
and predict their physiochemical … explorer, Pre ADMET prediction and Lazar toxicity prediction. …
Synthesis, in vitro cytotoxicity, ADME, and molecular docking studies of benzimidazole‐bearing furanone derivatives
… carbenes; benzimidazole-based piperidine derivatives and … of furanone derivatives containing
benzimidazole core and their … ADME predictions and in silico pharmacokinetic properties …
benzimidazole core and their … ADME predictions and in silico pharmacokinetic properties …
[PDF][PDF] Synthesis, molecular docking, in silico ADME and antimicrobial activity studies of some new benzimidazole-triazole derivatives
… In this study, 10 new triazole bearing benzimidazole derivatives were designed and synthesized,
and their structures were elucidated by IR, 1H NMR, 13C NMR, mass spectral analysis, …
and their structures were elucidated by IR, 1H NMR, 13C NMR, mass spectral analysis, …