[HTML][HTML] Clinical management of adults and children with multidrug-resistant and extensively drug-resistant tuberculosis

K Dheda, KC Chang, L Guglielmetti, J Furin… - Clinical Microbiology …, 2017 - Elsevier
… Thus, clofazimine and linezolid are now part of the core MDR-TB drugs (group C). In case
of drug resistance or inability to tolerate this regimen it is suggested that a drug from group D2 …

Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy

S Rheims, M Cucherat, A Arzimanoglou… - PLoS medicine, 2008 - journals.plos.org
… partial epilepsy in both children and adults. The … adults and children with drug-resistant
partial epilepsy in 32 RCTs. The treatment effect was significantly lower in children than in adults (…

Multidrug-and extensively drug-resistant tuberculosis in Africa and South America: epidemiology, diagnosis and management in adults and children

HS Schaaf, AP Moll, K Dheda - Clinics in chest medicine, 2009 - chestmed.theclinics.com
Children usually have transmitted drug resistance; they rarely develop drug resistance because
… Table 2 summarizes results of drug resistance surveys in children reported since 2000. …

Transmitted drug resistance among recently diagnosed adults and children in São Paulo, Brazil

PMS Guimarães, JLP Ferreira, LPO Coelho… - AIDS research and …, 2015 - liebertpub.com
Transmitted drug resistance mutations (TDRM) have been a constant threat to treatment
efficacy. We evaluated TDRM in plasma RNA of 217 antiretroviral therapy-naive patients from …

Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa

TS Boender, CM Kityo, RS Boerma… - Journal of …, 2016 - academic.oup.com
… ART guidelines for adults and older children are desired to facilitate the transition from
paediatric to adult care, we compared drug resistance rates and patterns in adults and children. In …

HIV-1 drug resistance profiles in children and adults with viral load of< 50 copies/ml receiving combination therapy

M Hermankova, SC Ray, C Ruff, M Powell-Davis… - Jama, 2001 - jamanetwork.com
… One plasma clone (4.4) lacked any drug resistance mutations and showed a close … drug
resistance via amplification and sequencing of HIV-1 was attempted in 12 adults and 8 children

In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia

J Styczynski, R Pieters, DR Huismans… - British journal of …, 2000 - Wiley Online Library
… In conclusion, we have found that adults with ALL were more drug resistant than children.
This might contribute to the difference in outcome between those age groups of patients with …

Management of young children in contact with an adult with drug-resistant tuberculosis, France, 2004–2008

M Tochon, E Bosdure, M Salles… - … of tuberculosis and …, 2011 - ingentaconnect.com
… starting treatment only after drug susceptibility testing (… children aged <2 years in contact
with a TB patient, to avoid the occurrence of TB disease. The drug resistance status of the adult

Impact of drug resistance on clinical outcome in children with tuberculous meningitis

JA Seddon, DH Visser, M Bartens… - The Pediatric …, 2012 - journals.lww.com
… tuberculosis strain and clinical phenotype has been explored in both adults and children
and drug resistance pattern is complex, but a strong association exists between drug resistance

… strand transfer inhibitor drug resistance mutations among children and adults on ART in Tanzania: findings from a national representative HIV drug resistance survey

D Kamori, G Barabona, J Rugemalila… - Journal of …, 2023 - academic.oup.com
… The age and HVL differences among children and adults were assessed using the Mann–…
of acquired drug resistance at early and late timepoints among children and adults by HVL …