Aerosol drug delivery: developments in device design and clinical use

MB Dolovich, R Dhand - The Lancet, 2011 - thelancet.com
effect. Patients and caregivers must use and maintain these aerosol drug delivery devices
… are used for aerosol delivery. In a 2005 systematic review, the authors concluded that these …

The mask for noninvasive ventilation: principles of design and effects on aerosol delivery

DR Hess - Journal of aerosol medicine, 2007 - liebertpub.com
… commercially available system designed specifically for aerosol delivery during NPPV with
… for aerosol delivery during NPPV is not nearly as mature as the evidence for aerosol delivery

Improving pharmaceutical aerosol delivery during noninvasive ventilation: effects of streamlined components

PW Longest, L Golshahi, M Hindle - Annals of biomedical engineering, 2013 - Springer
… Furthermore, the Optiflow nasal cannula is a gas-delivery device and was not designed for
aerosol delivery. These selected existing components are likely the best case for delivering a …

[HTML][HTML] Effect of nebulizer designs on aerosol delivery during non-invasive mechanical ventilation: a modeling study of in vitro data

H Saeed, AA Elberry, AS Eldin, H Rabea… - Pulmonary …, 2017 - Springer
… Nebulizers used to deliver aerosol during non-invasive mechanical ventilation (NIV) have …
designs. This study aimed to determine the effect of nebulizer deign on aerosol delivery in NIV. …

Influence of mouthpiece geometry on the aerosol delivery performance of a dry powder inhaler

MS Coates, HK Chan, DF Fletcher, H Chiou - Pharmaceutical research, 2007 - Springer
effect of mouthpiece geometry on the overall performance of a dry powder inhaler (Aerolizer
® ). Specifically, how design … area, and the subsequent effects on throat deposition and …

Aerosol delivery device selection for spontaneously breathing patients: 2012

A Ari, RD Restrepo - Respiratory care, 2012 - rc.rcjournal.com
… The conventional pMDI has a press-and-inhale design, … in the delivery of corticosteroids,
due to the side effects of steroid … larger dead volume reduces aerosol delivery to infants. The …

Aerosol delivery devices in the treatment of asthma

DR Hess - Respiratory care, 2008 - rc.rcjournal.com
… device for aerosol delivery. There are press-and-breathe and breath-actuated pMDI designs.
… I looked only at the effects of the use of heliox to deliver aerosolized bronchodilators in the …

Aerosols for macromolecule delivery: Design challenges and solutions

G Taylor, M Gumbleton - American Journal of Drug Delivery, 2004 - Springer
… Adverse effects and intolerance with nasal absorption enhancers have hampered progress
… the aerosol, since inhalation flow rate, inhalation volume, and point of aerosol delivery during …

CFD guided optimization of nose-to-lung aerosol delivery in adults: effects of inhalation waveforms and synchronized aerosol delivery

R Dutta, B Spence, X Wei, S Dhapare, M Hindle… - Pharmaceutical …, 2020 - Springer
… This dual nebulizer design allows for … effects of aerosol delivery synchronization and inhaled
flow rates on the regional deposition and lung delivery efficiencies for EEG aerosol delivery

Dry powder aerosol delivery systems: current and future research directions

HK Chan - Journal of aerosol medicine, 2006 - liebertpub.com
… particle size fractions of an aerosol can now be measured … to understand how the inhaler
design (such as mouthpiece, grid … Fundamental study of the effects of RH on adhesion due to …