Aerosol delivery to children

ML Everard - Pediatric annals, 2006 - journals.healio.com
… has evolved with specific defense mechanisms designed to minimize the probability of …
brief history of aerosol therapy, the reasons for using the inhaled route, basic principles that …

A path forward in the development of new aerosol drug delivery devices for pediatrics

JA O'Neil, LA Villasmil-Urdaneta - Respiratory Medicine, 2023 - Elsevier
… These losses can contribute to low dosing efficiency and significant variability in dosing,
making the device-facemask design integration important for maximizing aerosol delivery. As …

Aerosol delivery to ventilated newborn infants: historical challenges and new directions

J Mazela, RA Polin - European journal of pediatrics, 2011 - Springer
… Based upon what we have learned from the literature, future research in this area should
focus on designing appropriate aerosol delivery systems for ventilated neonates that efficiently …

Aerosols in pharmaceutical product development

PK Deb, SN Abed, H Maher, A Al-Aboudi… - Drug Delivery …, 2020 - Elsevier
… The devices used for aerosol delivery comprise majorly the small-volume nebulizers, pMDIs
… Despite the usual use of metal materials to design an aerosol container, plastic containers …

Adaptive Aerosol Delivery (AAD®) technology

J Denyer, K Nikander, NJ Smith - Expert opinion on drug delivery, 2004 - Taylor & Francis
… The AAD systems have been designed to adapt delivery of aerosol to the patient’s … system
targets aerosol delivery into the first 50% of a patient’s inhalation, and is designed to deliver a …

Variation in pediatric aerosol delivery: importance of facemask

GC Smaldone, E Berg, K Nikander - Journal of aerosol medicine, 2005 - liebertpub.com
… (VHC), facemask designs, and the seal of facemasks upon faces can be tested. This paper
asks the following questions regarding aerosol delivery via facemask for pediatric patients: …

Delivery of biotherapeutics by inhalation aerosol

RW Niven - Critical Reviews™ in Therapeutic Drug Carrier …, 1995 - dl.begellhouse.com
… ‘3“ However, these devices are designed to produce a fairly crude aerosol with droplet sizes
… However, it was concluded that aerosol delivery efficiency was low. To overcome the low …

Pulmonary drug delivery: from generating aerosols to overcoming biological barriers—therapeutic possibilities and technological challenges

CA Ruge, J Kirch, CM Lehr - The lancet Respiratory medicine, 2013 - thelancet.com
… Although impressive progress has been made in the aerosol component, our understanding
of, and the possibilities to control, the processes after aerosol deposition at the air–blood …

[HTML][HTML] Inhalable nanoparticulate powders for respiratory delivery

P Muralidharan, M Malapit, E Mallory… - … , Biology and Medicine, 2015 - Elsevier
delivery systems. This comprehensive review describes and discusses the current status,
drug design and modification for targeted delivery … century and antiseptic aerosol therapy was …

[PDF][PDF] Device selection and outcomes of aerosol therapy: Evidence-based guidelines

DR Hess, P Anderson, R Dhand, JL Rau… - Chest, 2005 - academia.edu
… Evidence-based guidelines for the selection of the appropriate aerosol deliveryaerosol
delivery devices in the ED met the criteria for inclusion in the analysis. All used a parallel design