Afatinib, erlotinib and gefitinib in the first-line therapy of EGFR mutation-positive lung adenocarcinoma: a review
J Köhler, M Schuler - Onkologie, 2013 - karger.com
… -cell lung cancer after failure of erlotinib, gefitinib, or both, and one … afatinib (BIBW 2992)
in patients with advanced non-small cell lung cancer after prior chemotherapy/erlotinib/gefitinib …
in patients with advanced non-small cell lung cancer after prior chemotherapy/erlotinib/gefitinib …
Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis
… that afatinib had greater efficacy than gefitinib or erlotinib in … However, afatinib was more
effective than erlotinib as second-… rate of afatinib was comparable to that of erlotinib but higher …
effective than erlotinib as second-… rate of afatinib was comparable to that of erlotinib but higher …
[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib
Y Kim, SH Lee, JS Ahn, MJ Ahn… - Cancer Research and …, 2019 - synapse.koreamed.org
… of clinical use of three EGFR TKIs (afatinib, gefitinib, and erlotinib). We found that gefitinib
was more commonly used than erlotinib or afatinib in Korea, especially for elderly, which may …
was more commonly used than erlotinib or afatinib in Korea, especially for elderly, which may …
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of …
VA Miller, V Hirsh, J Cadranel, YM Chen, K Park… - The lancet …, 2012 - thelancet.com
… Thus, we undertook this phase 2b/3 study of afatinib in … 12 weeks of previous erlotinib or
gefitinib treatment, a group for … to be less sensitive to erlotinib and gefitinib. Patients did not need …
gefitinib treatment, a group for … to be less sensitive to erlotinib and gefitinib. Patients did not need …
Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene mutations
P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… studies comparing gefitinib, erlotinib, and afatinib. … While gefitinib, erlotinib, and afatinib have
proven efficacy in patients with … the efficacy of erlotinib, gefitinib, and afatinib in patients with …
proven efficacy in patients with … the efficacy of erlotinib, gefitinib, and afatinib in patients with …
Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations
W Liang, X Wu, W Fang, Y Zhao, Y Yang, Z Hu, C Xue… - PloS one, 2014 - journals.plos.org
… The current study indicated that erlotinib, gefitinib, afatinib and icotinib … Erlotinib and afatinib
revealed potentially better efficacy but significant higher toxicities compared with gefitinib …
revealed potentially better efficacy but significant higher toxicities compared with gefitinib …
[HTML][HTML] Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX …
… erlotinib/gefitinib. This phase III trial prospectively assessed whether continued irreversible
ErbB-family blockade with afatinib … resistance to erlotinib/gefitinib and afatinib monotherapy. …
ErbB-family blockade with afatinib … resistance to erlotinib/gefitinib and afatinib monotherapy. …
Comparing the effects of afatinib with gefitinib or Erlotinib in patients with advanced-stage lung adenocarcinoma harboring non-classical epidermal growth factor …
… We surveyed the effectiveness of afatinib and gefitinib/erlotinib … However, Chiu et al.
reported gefitinib and erlotinib were … the efficacy of gefitinib/erlotinib and afatinib in patients with …
reported gefitinib and erlotinib were … the efficacy of gefitinib/erlotinib and afatinib in patients with …
Which is better EGFR-TKI followed by osimertinib: afatinib or gefitinib/erlotinib?
M Tamiya, A Tamiya, H Suzuki, K Moriizumi… - Anticancer …, 2019 - ar.iiarjournals.org
… Afatinib may overcome tumor heterogeneity, leading to T790M colonal purity. We aimed to
determine whether NSCLC treatment with afatinib followed by osimertinib (afatinib … afatinib …
determine whether NSCLC treatment with afatinib followed by osimertinib (afatinib … afatinib …
… of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O desmethyl metabolites of erlotinib and gefitinib in human plasma
RW Sparidans, H Rosing, JJM Rood… - … of Chromatography B, 2016 - Elsevier
… afatinib, erlotinib, gefitinib and encorafenib and the Odesmethyl metabolites of erlotinib
and gefitinib … isotopically labeled internal standard of afatinib, erlotinib, gefitinib and OSI-420. …
and gefitinib … isotopically labeled internal standard of afatinib, erlotinib, gefitinib and OSI-420. …