Why do some African children develop severe malaria?

B Greenwood, K Marsh, R Snow - Parasitology today, 1991 - Elsevier
… rate of severe malaria is in the region of 50%, then approximately 2% of clinical attacks of
malaria in African children are severe (Fig. 2). What is special about these children and how do …

The pathogenesis of severe malaria in African children

K Marsh, M English, J Crawley… - Annals of Tropical …, 1996 - Taylor & Francis
… processes leading to severe malaria are probably … African children. This review will
focus on the latter group as they account for around 90% of the worldwide load of severe-malarial

Combating severe malaria in African children

JG Breman, CC Campbell - Bulletin of the World Health …, 1988 - ncbi.nlm.nih.gov
… , diarrhoea and vaccinepreventable diseases, called the Africa Child Survival Initiative … in
13 African countries, 12 of whichare endemic for malaria. The project's malaria control strategy …

Indicators of life-threatening malaria in African children

K Marsh, D Forster, C Waruiru, I Mwangi… - New England journal …, 1995 - Mass Medical Soc
… the WHO guidelines on severe malaria that no single definition of severe disease will be …
African children: the first should aim to define in detail the pathophysiologic elements of severe

Severe malaria in children in areas with low, moderate and high transmission intensity in Uganda

R Idro, J Aloyo, L Mayende… - Tropical Medicine & …, 2006 - Wiley Online Library
… of children with severe malaria presenting with severe anaemia … children respectively in
the two areas. In the moderate transmission area, the proportion of patients with severe malaria

Severe malaria

NJ White - Malaria journal, 2022 - Springer
… more frequent in African children diagnosed with severe malaria. Approximately 6% of children
hospitalized with a diagnosis of severe falciparum malaria in Africa are also bacteraemic […

Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial

L Von Seidlein, R Olaosebikan… - Clinical Infectious …, 2012 - academic.oup.com
… outcome from severe malaria. … African children (<15 years) with severe malaria participated
in a randomized comparison of parenteral artesunate and parenteral quinine in 9 African

Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa

RW Snow, JA Omumbo, B Lowe, CS Molyneux… - The lancet, 1997 - thelancet.com
… that a child will be admitted to hospital with severe malaria before his or her 10th birthday. If
the epidemiologial features of severe malaria were consistent across sub-Saharan Africa we …

Pathophysiology of severe malaria in children

K Maitland, K Marsh - Acta tropica, 2004 - Elsevier
… central feature of severe malaria and the major … severe malaria through a series of clinical
scenarios that reflect more accurately the clinical diversity of severe malaria in African children. …

[HTML][HTML] Over-diagnosis and co-morbidity of severe malaria in African children: a guide for clinicians

S Gwer, P CHARLES RJC NEWTON… - The American journal …, 2007 - ncbi.nlm.nih.gov
… We initially searched for data on severe malaria among children in Africa, then studies
elsewhere, in adults or non-severe malaria if these were relevant. All abstracts were read; if there …