The genomic landscape of African populations in health and disease

CN Rotimi, AR Bentley, AP Doumatey… - Human molecular …, 2017 - academic.oup.com
genomic research in African ancestry populations is still in early stages, there are already
many examples of novel and African … Furthermore, the shorter haplotypes in African genomes

The genome landscape of indigenous African cattle

J Kim, O Hanotte, OA Mwai, T Dessie, S Bashir… - Genome biology, 2017 - Springer
… of African cattle genetic variation by sequencing 48 genomes from five indigenous populations
and comparing them to the genomes … We find the highest genetic diversity among African

Genomic landscape of human diversity across Madagascar

D Pierron, M Heiske… - Proceedings of the …, 2017 - National Acad Sciences
Genomes Project (52) populations, to which we added several African populations (6,637
SNPs after pruning; populations … one east African population from the 1,000 Genomes Project; …

The potential of landscape genomics approach in the characterization of adaptive genetic diversity in indigenous goat genetic resources: a South African perspective

K Mdladla, EF Dzomba, FC Muchadeyi - Small Ruminant Research, 2017 - Elsevier
… of South Africa and the production and environmental landscape of … genomics are outlined
and the potential of landscape genomics in deciphering the genetic merits of South African

Genomic landscape of colorectal carcinoma in sub-Saharan Africa

AP Aldera, K Pillay, B Robertson, A Boutall… - Journal of Clinical …, 2023 - jcp.bmj.com
… seem to be uncommon in Africa. The high proportion of MSI … in Africa. The purpose of this
review is to summarise the current state of the molecular genetic landscape of CRC in Africa

Landscape genomics and pathway analysis to understand genetic adaptation of South African indigenous goat populations

K Mdladla, EF Dzomba, FC Muchadeyi - Heredity, 2018 - nature.com
African goat population. This study used a combination of multivariate statistics, landscape
genomics, and population genomics… in local indigenous goat populations. The three statistical …

Identification of Signatures of Positive Selection That Have Shaped the Genomic Landscape of South African Pig Populations

NL Hlongwane, EF Dzomba, K Hadebe… - Animals, 2024 - mdpi.com
… regions containing significant evidence of population-specific selection signatures were …
The population genomic approach utilised in this study allowed for the identification of genomic

The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia

L Deng, BP Hoh, D Lu, R Fu, ME Phipps, S Li… - Human genetics, 2014 - Springer
… Overall, our results supported the “Out of Africa” hypothesis since all the non-African
populations showed a significant decline of N e (Fig. 2b) suggesting they have experienced a …

[HTML][HTML] The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape

B Dobon, HY Hassan, H Laayouni, P Luisi… - Scientific reports, 2015 - nature.com
… In this study we present an extensive genome-wide data set characterizing East African
human genetic diversity in populations from Sudan, South Sudan and Ethiopia. We further …

Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting

P Musicha, NA Feasey, AK Cain… - Journal of …, 2017 - academic.oup.com
… settings, in sub-Saharan Africa molecular patterns of AMR are not well described. In this
study, we have begun to explore the population structure and molecular determinants of AMR …