Opinion statement Breast cancer (BC) under age 40 is a complex disease to manage due to
the additionally fertility-related factors to be taken in consideration. More than 90 % of young …

… But what evidence is there that these molecular phenotypes also modify response to …
High tumour proliferation is at best of no predictive value or is indicative of worse response in …

… Neo-adjuvant chemotherapy reduces tumour size and increases the numbers of patients
suitable for surgery, however no difference is seen by age for complete pathological response […

… age of the patient at diagnosis. Numerous studies have shown very different breast cancer
outcomes based on patient age… within the context of age because breast cancer is a very …

… age ≤ 40) women who developed breast cancer experienced the largest relative declines in
HRQoL (as compared with middle-aged … differed in their response to breast cancer than did …

… are routinely done for all invasive breast cancer, independent of age. However, different
treatment after recurrence [2, 271, and different response to hormonal therapy [4], may explain …

… For 466 of the 4467 samples in our cohort information on age and pathological complete
response (pCR) after neoadjuvant treatment was available. We observed no overall effect on …

… is phenotypically diverse in prognosis and response to treatment. This diversity has
resulted in the delineation of a molecular taxonomy of the disease. In 2000, gene expression …

… The survey elicits information about the first indication of breast cancer (with response
categories that include screening mammogram, lump detected by a physician, self-discovered …

… breast cancer are diagnosed before the age of 40 years, and this disease accounts for more
than 40% of all cancer in women in this age … analysis has shown younger age to be an …