Therapeutic innovations in endocrine diseases–part 3: temozolomide and future therapeutics for aggressive pituitary tumors and carcinomas

H Lasolle, G Raverot - La Presse Médicale, 2016 - Elsevier
tumors should be considered as more than a simple endocrine disorder. Descriptions of
aggressive pituitary tumors and pituitary … the successful treatment of pituitary carcinomas using …

The microenvironment of pituitary tumors—biological and therapeutic implications

MD Ilie, A Vasiljevic, G Raverot, P Bertolino - Cancers, 2019 - mdpi.com
… has been made and this has started to pave the way for the development of innovative
therapeutics, this review highlights the need to further improve our knowledge of the complex …

Current and emerging medical therapies in pituitary tumors

N Sahakian, F Castinetti, T Brue, T Cuny - Journal of clinical medicine, 2022 - mdpi.com
pituitary neuroendocrine tumors (PitNETs), or simply as pituitary tumors (PT) [1] represent
benign tumors … Their treatment may involve a combination of surgery, medical therapies (such …

Aggressive and malignant pituitary tumours: state-of-the-art

D Dworakowska, AB Grossman - Endocrine-related cancer, 2018 - erc.bioscientifica.com
… diagnostic process for aggressive pituitary tumours and PC was … aggressive pituitary tumour
be considered in patients with a radiologically invasive tumour and unusually rapid tumour

Recent therapeutic advances in pituitary carcinoma

IJ Robertson, TA Gregory… - Journal of …, 2023 - meridian.allenpress.com
… [3] Less commonly, these tumors are locally destructive, treatment resistant, and have high
… as aggressive pituitary tumors (APTs). [4] In the most extreme cases, 0.1–0.2% of tumors

Temozolomide treatment can improve overall survival in aggressive pituitary tumors and pituitary carcinomas

H Lasolle, C Cortet, F Castinetti, L Cloix… - European Journal of …, 2017 - academic.oup.com
… of therapies or recur during follow-up and are considered as aggressive with unclear
epidemiology (2). For those with atypical morphological features suggestive of aggressive behavior …

Clinical efficacy of temozolomide and its predictors in aggressive pituitary tumors and pituitary carcinomas: a systematic review and meta-analysis

M Luo, Y Tan, W Chen, B Hu, Z Wang, D Zhu… - Frontiers in …, 2021 - frontiersin.org
Pituitary adenomas (PAs) are common intracranial tumors … small number of patients with
aggressive pituitary tumors (APTs) … , ~0.2% of pituitary adenomas are characterized as pituitary

From Genes to Therapy: Pituitary Adenomas in the Era of Precision Medicine

C Toader, N Dobrin, CI Tataru, RA Covache-Busuioc… - Biomedicines, 2023 - mdpi.com
… We highlight potential breakthroughs and innovations for a more effective management and
treatment of pituitary adenomas, while shedding light on the ongoing need for research and …

Advances and controversies in the classification and grading of pituitary tumors

ER Laws, DL Penn, CS Repetti - Journal of Endocrinological Investigation, 2019 - Springer
… for distinguishing aggressive pituitary adenomasinnovative ideas and perspectives resulting
in improved genetic and molecular research and the discovery of better medical therapies

New Developments in the Treatment and Management of Pituitary Disorders

N Hamblin, G Monteleone - Journal of Endocrinology Research, 2024 - ojs.sp.sg
… of pituitary carcinomas and other aggressive pituitary tumors. The results suggest that a
multimodal approach, combining surgery, radiation therapy, and targeted therapies, … innovations, …