… aggressive variants, the treatment of these patients is often inadequate or suboptimal. The
aim of this review is to describe the aggressive variants of … implications these variants have on …

… Results of our trend analyses indicate that the incidence of the aggressive variants, … in the
literature, the increase in incidence of the aggressive variants may be due to better detection; it …

… %, 3%, and 6% of aggressive variants of PTC, respectively. The mutation … , aggressive
variants of PTC had higher BRAF and lower NRAS mutation prevalence than other thyroid cancers…

… be associated with more aggressive tumor behavior. … variants of well-differentiated papillary
thyroid cancer are all potentially more aggressive than conventional papillary thyroid cancer. …

… Importantly, in the absence of invasive features, several presumed aggressive variants do
not actually have worse prognosis than cPTC lesions and thus, we argue that this subset of …

… prognostic implications of more aggressive variants are far less … for aggressive variants of
papillary thyroid carcinoma (PTC). … Other known, aggressive thyroid cancer subtypes with too …

… ATC is the most aggressive form of thyroid malignancy and of solid tumour, in general. ATC
is a very rare tumour, and it accounts for <5% of all thyroid cancers with a peak incidence in …

… thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) … is one of the main features
characterizing aggressive TC. The … been approved for the therapy of aggressive radioiodine (RAI)-…

… This review will focus on the clinical and pathologic characteristics of the more
aggressive variants and the associated patient outcomes. It will include diffuse sclerosing …

… Herein, we review the literature regarding these aggressive thyroid cancers and
emphasize notable phenotypic characteristics that can help with their cytologic diagnosis. …