… post-infarction heart failure on our health care system. Therapies specifically designed to
limit ventricular remodeling in elderly populations and stem the tide of increasing heart failure …

… LV undergoes a lifelong remodeling. In an elderly population, various age-related changes
of the cardiovascular system occur ranging from reduced heart rate and impaired diastolic …

… aging leads to a continuous rise in wall stress that is not normalized by ventricular remodeling…
These two independent processes appear to be responsible for the onset of heart failure in …

… However, increased LV mass can result from a variety of different remodeling … remodeling
pattern observed in normally aging individuals over the life course is a concentric remodeling …

… Aging Processes involved in maladaptive ventricular remodeling are age dependent, and
most patients with heart disease are older. Indeed, a caveat to translating preclinical results …

… the heart. We hypothesized that estrogen could attenuate the remodeling changes of the aged
heart, … This study evaluated the effects of aging and estrogen on left ventricular weight and …

… that remodeling of LV structure with age in both genders is characterized mainly by a shortening
of the left ventricle … The aging heart is subject to an increasing systolic load imposed by …

… of age-based ventricular remodeling is likely also related to the well-described coupling of
ventricular … Indeed, our ventricular findings were observed independent from, but also in the …

… size (referred to as concentric remodeling when LV mass is normal). The left ventricular
remodeling pattern may be associated with an increase in left ventricular mass (referred to as …

… The first phenotype corresponds to the healthy aging heart. In the normal process of aging,
… LV mass also decreases with age, but at a much slower pace, which results in concentric …