过去一年中添加的文章，按日期排序
The immunoreactive signature of monocyte-derived dendritic cells from patients with Down syndrome
K Nakashima, T Imai, A Shiraishi… - Clinical and …, 2024 - academic.oup.com
2 天前 - … Cellular senescence is an irreversible condition in which … Toll-like receptor (TLR)
pathways. These data indicate that MoDCs … As observed in this study, aging affects the pool of …
pathways. These data indicate that MoDCs … As observed in this study, aging affects the pool of …
[HTML][HTML] Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration
N Saurat, AP Minotti, MT Rahman, T Sikder, C Zhang… - Cell Stem Cell, 2024 - cell.com
4 天前 - … but it is unclear which genes and pathways regulate this process during normal
aging. To address this, past studies generated induced neurons via direct reprogramming from …
aging. To address this, past studies generated induced neurons via direct reprogramming from …
[HTML][HTML] Single-cell landscape of immunological responses in elderly patients with sepsis
W He, C Yao, K Wang, Z Duan… - Immunity & …, 2024 - immunityageing.biomedcentral.com
6 天前 - … To reveal the impact of sepsis and aging on immune cell composition, we compared
… and TNF signaling pathways. In addition, the cellular senescence pathway was enriched in …
… and TNF signaling pathways. In addition, the cellular senescence pathway was enriched in …
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis
X Wang, K Wang, W Mao, Z Fan, T Liu, R Hong… - Environmental …, 2024 - Elsevier
6 天前 - … Finally, by inhibiting the ferroptosis pathway with ferrostatin… Cellular senescence
encompasses a spectrum of distinct … and mitigated cellular aging in MC3T3-E1 cells. This …
encompasses a spectrum of distinct … and mitigated cellular aging in MC3T3-E1 cells. This …
A new gene signature for endothelial senescence identifies self‐RNA sensing by retinoic acid‐inducible gene I as a molecular facilitator of vascular aging
J Guduric‐Fuchs, E Pedrini, PM Bertelli… - Aging …, 2024 - Wiley Online Library
6 天前 - … showed that endothelial cell senescence hallmarks include … endothelial cells
underscored senescence as a key pathway … acid sensing pathways play a role in cell senescence, …
underscored senescence as a key pathway … acid sensing pathways play a role in cell senescence, …
[HTML][HTML] NLRP1 inflammasome promotes senescence and senescence-associated secretory phenotype
I Muela-Zarzuela, JM Suarez-Rivero… - Inflammation …, 2024 - Springer
6 天前 - … Senescence is a cellular aging-related process triggered by … changes associated
with cellular senescence, which has … signaling pathways such as the p53 and p16 pathways, …
with cellular senescence, which has … signaling pathways such as the p53 and p16 pathways, …
[HTML][HTML] Bioinformatic analysis combined with immune infiltration to explore osteoarthritis biomarkers and drug prediction
Y Liu, W Jiang, J Huang, L Zhong - Medicine, 2024 - journals.lww.com
7 天前 - … Cellular senescence is a cyclic form of the cell cycle in … age, that is, aging stimulates
cartilage degradation. Conversely … in joint cells associated with senescence characteristics, …
cartilage degradation. Conversely … in joint cells associated with senescence characteristics, …
Endocrine-exocrine miR-503-322 drives aging-associated pancreatitis via targeting MKNK1 in acinar cells
Y Zhu, K Liu, T Lv, W Tang, Y Zhang, X Xiao, Y Li… - 2024 - researchsquare.com
7 天前 - … Here, we demonstrate that senescent β-cells of 22 … During 23 physiological aging,
senescent β-cells increase … -eIF4E pathway to inhibit 235 zymogen secretion and acinar-cell …
senescent β-cells increase … -eIF4E pathway to inhibit 235 zymogen secretion and acinar-cell …
[HTML][HTML] Fibronectin and vitronectin alleviate adipose-derived stem cells senescence during long-term culture through the AKT/MDM2/P53 pathway
P Tragoonlugkana, C Pruksapong, P Ontong… - Scientific Reports, 2024 - nature.com
8 天前 - … molecules on cellular senescence, the aging-related cellular signaling pathway
was investigated. The use of adhesion molecules is expected to promote cell adhesion, …
was investigated. The use of adhesion molecules is expected to promote cell adhesion, …
[HTML][HTML] Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice
SJM Stefens, N van Vliet, A IJpma, J Burger, Y Li… - npj Aging, 2024 - nature.com
8 天前 - … of the TGF-β pathway in establishing the senescence phenotype and indicate
that targeting of the TGF-β pathway is effective in alleviating the senescent phenotype. …
that targeting of the TGF-β pathway is effective in alleviating the senescent phenotype. …