Stimulation of human and rat alveolar macrophages by urban air particulates: effects on oxidant radical generation and cytokine production
S Becker, JM Soukup, MI Gilmour, RB Devlin - Toxicology and applied …, 1996 - Elsevier
… particulates. Supernatants of AM exposed to the indicated concentrations of UAP particles
… particles collected from the ambient air may also contain mi- preparations used in this study …
… particles collected from the ambient air may also contain mi- preparations used in this study …
Systemic inflammatory response induced by particulate matter air pollution: the importance of bone-marrow stimulation
SF Eeden, JC Hogg - … of Toxicology and Environmental Health, Part …, 2002 - Taylor & Francis
… We conclude that exposure to ambient particulate matter air … stimulate the bone marrow
to release leukocytes and platelets. We postulate that this systemic response to particulate air …
to release leukocytes and platelets. We postulate that this systemic response to particulate air …
Phagocytosis of particulate air pollutants by human alveolar macrophages stimulates the bone marrow
H Mukae, JC Hogg, D English… - … of Physiology-Lung …, 2000 - journals.physiology.org
… In the present study, we used TNF-α as a marker of human AM stimulation and the rabbit
model to determine the collective effect of the AM-derived mediators on the bone marrow. A …
model to determine the collective effect of the AM-derived mediators on the bone marrow. A …
Cytokines Involved in the Systemic Inflammatory Response Induced by Exposure to Particulate Matter Air Pollutants (PM10)
SF van EEDEN, WC Tan, T Suwa, H Mukae… - American journal of …, 2001 - atsjournals.org
… Military recruits exposed to high concentrations of particulate matter air pollution during the
… with bone marrow stimulation (8). We postulate that atmospheric particles stimulate AM to …
… with bone marrow stimulation (8). We postulate that atmospheric particles stimulate AM to …
Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro
T Ohtoshi, H Takizawa, H Okazaki, S Kawasaki… - Journal of Allergy and …, 1998 - Elsevier
… Objective: We studied the effect of suspended particulate matter … colony-stimulating factor
(GM-CSF) by human airway epithelial … air pollutants, stimulated cytokine production by human …
(GM-CSF) by human airway epithelial … air pollutants, stimulated cytokine production by human …
Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies
S Becker, S Mundandhara, RB Devlin… - Toxicology and applied …, 2005 - Elsevier
… stimulated previously unexposed and diesel exposed cells were the same. In contrast, AM
exposed to ambient air pollution particles … production by air ambient pollution particles, but not …
exposed to ambient air pollution particles … production by air ambient pollution particles, but not …
Effects of metals within ambient air particulate matter (PM) on human health
LC Chen, M Lippmann - Inhalation toxicology, 2009 - Taylor & Francis
… effects caused by inhalation of ambient air particulate matter (PM) containing metals, … )
human and laboratory animal exposures to concentrated ambient particles (CAPs), and (2) human …
human and laboratory animal exposures to concentrated ambient particles (CAPs), and (2) human …
Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages
S Becker, JM Soukup, JE Gallagher - Toxicology in vitro, 2002 - Elsevier
… The data presented are derived from stimulation of 2×10 5 cells with 100 μg particles since
only a few of the dusts were reactive at the lower particle amounts (30 and 10 μg) As can be …
only a few of the dusts were reactive at the lower particle amounts (30 and 10 μg) As can be …
The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses
… Ambient air particles and DEP may suppress TNF-α release … human AM stimulated with
different signal transduction agonists was measured. Comparison across several known stimuli …
different signal transduction agonists was measured. Comparison across several known stimuli …
Response of human alveolar macrophages to ultrafine, fine, and coarse urban air pollution particles
S Becker, JM Soukup, C Sioutas… - Experimental lung …, 2003 - Taylor & Francis
… of air pollution particles in stimulating inflammation has been emphasized both in animal
models and in human … with UF, fine, and coarse particles, collected simultaneously from 2 urban …
models and in human … with UF, fine, and coarse particles, collected simultaneously from 2 urban …
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