Human alveolar macrophage responses to air pollution particulates are associated with insoluble components of coarse material, including particulate endotoxin
JM Soukup, S Becker - Toxicology and applied pharmacology, 2001 - Elsevier
… When AM were stimulated with 100 μg/ml isPM10, polymixin … air particles deliver more ETOX
to the lower airways than air … preferentially deposit coarse particles in the airways in sites of …
to the lower airways than air … preferentially deposit coarse particles in the airways in sites of …
Particulate matter air pollution stimulates monocyte release from the bone marrow
Y Goto, H Ishii, JC Hogg, CH Shih, K Yatera… - American journal of …, 2004 - atsjournals.org
… This model is a useful experimental tool to identify the AM-derived mediators responsible
for the systemic response (BM stimulation) of particulate matter air pollution (15). We have …
for the systemic response (BM stimulation) of particulate matter air pollution (15). We have …
Particulate matter induces cytokine expression in human bronchial epithelial cells
T Fujii, S Hayashi, JC Hogg, R Vincent… - American journal of …, 2001 - atsjournals.org
… fraction of the EHC-93 particles has a much smaller stimulating effect on the HBEC than …
dissimilar from the particles we used, which were ambient air pollution particles collected over a …
dissimilar from the particles we used, which were ambient air pollution particles collected over a …
Oxidant mechanisms in response to ambient air particles
B González-Flecha - Molecular aspects of medicine, 2004 - Elsevier
… released from PM-stimulated macrophages, and neural stimulation after particle deposition
in the lungs. The involvement of ROS in each one of these possible pathways is discussed. …
in the lungs. The involvement of ROS in each one of these possible pathways is discussed. …
The Effect of Repeated Exposure to Particulate Air Pollution (PM10) on the Bone Marrow
H Mukae, R Vincent, K Quinlan, D English… - American Journal of …, 2001 - atsjournals.org
… We also show that this bone marrow stimulation is related to the amount of particles …
the pathogenesis of the cardiopulmonary diseases associated with particulate air pollution. …
the pathogenesis of the cardiopulmonary diseases associated with particulate air pollution. …
Health effects of ambient particulate matter—biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures
KL Maier, F Alessandrini, I Beck-Speier… - Inhalation …, 2008 - Taylor & Francis
… Particulate matter is a complex group of air pollutants that vary in size. Particles between 10
… Based on the finding that DEP enhances the expression of COX2 after stimulation with LPS …
… Based on the finding that DEP enhances the expression of COX2 after stimulation with LPS …
Coarse (PM 2.5-10), fine (PM 2.5), and ultrafine air pollution particles induce/increase immune costimulatory receptors on human blood-derived monocytes but not on …
S Becker, J Soukup - … of toxicology and environmental health Part A, 2003 - Taylor & Francis
… In parallel, both cell types were stimulated alone in … We found that pollution particles
collected from the ambient air … In contrast to size-fractionated ambient air PM, neither diesel soot …
collected from the ambient air … In contrast to size-fractionated ambient air PM, neither diesel soot …
[HTML][HTML] Effects of diesel exhaust particles on human lung epithelial cells: an in vitro study
G Mazzarella, F Ferraraccio, MV Prati, S Annunziata… - Respiratory …, 2007 - Elsevier
… stimulating their production and release of proinflammatory cytokines. We may therefore
confirm that ECs represent a primary target of air … in PM 1.0 -stimulated human lung Type II ECs …
confirm that ECs represent a primary target of air … in PM 1.0 -stimulated human lung Type II ECs …
Airborne particulate matter modulates the production of reactive oxygen species in human polymorphonuclear granulocytes
B Hitzfeld, KH Friedrichs, J Ring, H Behrendt - Toxicology, 1997 - Elsevier
… of particles. Our study shows that only organic substances adsorbed to particles stimulate
LCL. … Air pollutants such as ambient air particles, fly ash and heavy metals have cytotoxic and …
LCL. … Air pollutants such as ambient air particles, fly ash and heavy metals have cytotoxic and …
Pro‐inflammatory effects of Dunkerque city air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture
Z Dagher, G Garçon, P Gosset, F Ledoux… - Journal of Applied …, 2005 - Wiley Online Library
… Stimulation of human and rat alveolar macrophages by urban air particulates: effect on oxidant
radical … Differential particulate air pollution induced oxidant stress in human granulocytes, …
radical … Differential particulate air pollution induced oxidant stress in human granulocytes, …