Airborne fine particulate matter induces multiple cell death pathways in human lung epithelial cells

X Deng, F Zhang, L Wang, W Rui, F Long, Y Zhao… - Apoptosis, 2014 - Springer
… by airborne fine particulate matter (PM) with a mean diameter of less than 2.5 μm (PM 2.5 ) in
human lung epithelial A549 cells, which could potentially lead to cell … in A549 cells. Much to …

Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic …

A Valavanidis, K Fiotakis… - Journal of Environmental …, 2008 - Taylor & Francis
… to produce ROS in the cellular environment. Many recent … , play an important role of oxidative
cellular damage through the … oxidative stress in inducing cellular damage and subsequently …

Genotoxicity of airborne particulate matter: the role of cellparticle interaction and of substances with adduct-forming and oxidizing capacity

HL Karlsson, J Nygren, L Möller - Mutation Research/Genetic Toxicology …, 2004 - Elsevier
… the genotoxicity of PM in relation to particlecell interactions and to study the effect of … and
that cells interacting with PM suffered more DNA single-strand breaks relative to other cells. …

Airborne particulate matter and mitochondrial damage: a cross-sectional study

L Hou, ZZ Zhu, X Zhang, F Nordio, M Bonzini… - Environmental …, 2010 - Springer
cellular response to the increased oxidative stress caused by exposure to PM. This response
has been suggested to have a dual role in cells … to meet the need for cell survival, including …

Airborne particulate matter (PM2. 5) triggers autophagy in human corneal epithelial cell line

Q Fu, D Lyu, L Zhang, Z Qin, Q Tang, H Yin, X Lou… - Environmental …, 2017 - Elsevier
… nature, increasing evidence suggests that particulate matter (PM), especially that less than
2.5 μm in diameter (referred to as PM2.5), plays a major role in cardiovascular and chronic …

Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models

Z Zheng, X Zhang, J Wang, A Dandekar, H Kim… - Journal of …, 2015 - Elsevier
… hepatocytes, macrophage cell line RAW264.7, and LX-2, a human HSC cell line that retains
… culture medium from RAW264.7 cells, but not hepatocytes or LX-2 cells, were increased in a …

Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways

EM Quezada-Maldonado, Y Sánchez-Pérez… - Environmental …, 2021 - Elsevier
… The precise mechanism by which PM is linked to cancer has not been completely described,
and the genotoxicity induced by PM exposure plays a relevant role in cell damage. In this …

Variations in reactive oxygen species generation by urban airborne particulate matter in lung epithelial cells—Impact of inorganic fraction

O Mazuryk, G Stochel, M Brindell - Frontiers in chemistry, 2020 - frontiersin.org
… is still a matter of various discussions. The influence of airborne particulate matter (PM)
and … inorganic components on biological function of human alveolar-like epithelial cells (A549) …

Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria

D Upadhyay, V Panduri, A Ghio… - … journal of respiratory cell …, 2003 - atsjournals.org
Airborne particulate matter (PM) increases morbidity and mortality resulting from
cardiopulmonary diseases including cancer. We hypothesized that PM is genotoxic to alveolar …

Oxidative potential versus biological effects: a review on the relevance of cell-free/abiotic assays as predictors of toxicity from airborne particulate matter

J Øvrevik - International journal of molecular sciences, 2019 - mdpi.com
Airborne particulate matter (PM) represents one of the major environmental risk factors
for disease and premature death worldwide, and has been associated with development or …