β-adrenoceptor responses of the airways: for better or worse?

KJ Broadley - European journal of pharmacology, 2006 - Elsevier
β 2 -adrenoceptor agonist are the influx of inflammatory cells, the late asthmatic response
and the airway hyperreactivity. A single dose of salbutamol failed to inhibit bronchoalveolar or …

Association of β2-Adrenoreceptor Variants with Bronchial Hyperresponsiveness

M Ulbrecht, MT Hergeth, M Wjst, J Heinrich… - … journal of respiratory …, 2000 - atsjournals.org
airway tone, the β 2 -adrenoreceptor is considered a candidate for bronchial hyperresponsiveness
… –q33 harboring the gene for the β 2 -adrenoreceptor in the genetics of asthma and …

Association of Persistent Bronchial Hyperresponsiveness with β2-Adrenoceptor (ADRB2) Haplotypes: A Population Study

M D'AMATO, LR Vitiani, G Petrelli… - … journal of respiratory …, 1998 - atsjournals.org
Bronchial hyperresponsiveness (BHR) is a hallmark of … Increasing attention is being focused
on the β 2 -adrenoceptor … features of asthma, including airways reactivity. To verify whether …

Airway hyperresponsiveness

PM O'Byrne, MD Inman - Chest, 2003 - Elsevier
… One specific gene polymorphism (Glu 27) of the nine identified of the β 2 -adrenoceptor
also has been associated with increased methacholine airway hyperresponsiveness, 30 while …

Long-Term Effects of a Long-Acting β2-Adrenoceptor Agonist, Salmeterol, on Airway Hyperresponsiveness in Patients with Mild Asthma

D Cheung, MC Timmers, AH Zwinderman… - … England Journal of …, 1992 - Mass Medical Soc
… effects on lung function and airway hyperresponsiveness, with particular attention to the …
β 2 -adrenoceptor agonist on bronchodilation and airway hyperresponsiveness in asthma. …

Molecular mechanisms of β2-adrenergic receptor function, response, and regulation

M Johnson - Journal of Allergy and Clinical Immunology, 2006 - Elsevier
… Preliminary data from Dutch families with asthma suggest that Gly 16 might be associated
with airway hyperreactivity. In addition, patients with significant nocturnal worsening of their …

Beyond the dogma: novel β2-adrenoceptor signalling in the airways

MA Giembycz, R Newton - European Respiratory Journal, 2006 - Eur Respiratory Soc
β 2 -adrenoceptor agonists is common in the management of asthma and airways
hyperresponsiveness (… short- and long-acting β 2 -adrenoceptor agonists to protect the airways

Asthma, allergy, and airway hyperresponsiveness are not linked to the β2-adrenoceptor gene

CW Emala, CK McQuitty, SM Eleff, P Hopkins-Price… - Chest, 2002 - Elsevier
… this gene and asthma, bronchial hyperresponsiveness, or allergy, none of … β 2 -adrenoceptor
gene with strong effect and asthma, allergy, or methacholine airway hyperresponsiveness

β2-Adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men

AA Litonjua, EK Silverman, KG Tantisira, D Sparrow… - Chest, 2004 - Elsevier
… Because airway hyperresponsiveness is an important intermediate phenotype in asthma,
we sought to determine whether β 2 -AR polymorphisms at positions 16 and 27, individually …

The role of alpha and beta adrenoceptors in airway hyperresponsiveness to histamine

C Jenkins, ABX Breslin, GE Marlin - Journal of allergy and clinical …, 1985 - Elsevier
… The effect of a spectfic cu,-adrenoceptor antagonist, prazosin… with nonspecific bronchial
hyperresponsiveness whose P&H … a-adrenoceptors in addition to /3-adrenoceptors in histamine-…