… ) in cystic fibrosis (CF) airway epithelial cells are associated with airway mucus hypersecretion…
stage of the disease, to severe airway obstruction with hyperviscous and adhesive airway …

… We now know that CF sputum contains very little mucin when compared to normal airway
mucus from subjects without lung disease or expectorated sputum from patients with chronic …

… natural progression of the airway mucus defect in cystic fibrosis (CF) … airway mucus
abnormalities. The KO rat exhibits decreased periciliary depth, hyperacidic pH, and increased mucus …

… Since the resulting progressive lung disease can lead to respiratory failure and ultimately
death, this review focuses on studies conducted on airway mucus, more specifically on …

… 4), which may have important clinical implications for the management of airway mucus
overproduction in CF. There is a CRE cis-site (−878/−871 nt) in the MUC5AC promoter and IL1β …

… The view proposed here is that the major effect of impaired CF airway mucus clearance is to
… compounds in airway mucus interdependent with mucins? Do altered CF mucus properties …

… Comprehensive treatment of cystic fibrosis includes … agents and clearance of mucus. Although
the dominant clearance … in clearing mucus from the airways of patients with cystic fibrosis, …

… Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic
fibrosis transmembrane conductance regulator expression. Am J Respir Cell Mol Biol 2005;32:453…

… Airway mucus secretion is a normal physiological process involved with homeostasis and
is a … However, mucus hypersecretion, with abnormal mucus consistency, causes airway …

… mucus in muco-obstructive lung diseases, eg, cystic fibrosis (… mucus layer onto the airway
surface with the formation of adherent mucus plaques and plugs, particularly in distal airways…