… airway organoids with the apical side externally exposed. These apical-out airway organoids
are … bronchial epithelial cells and differentiated in suspension to develop uniformly-sized …

… airway organoids as a model to study SARS-CoV-2 replication kinetics, tropism, and host
response (figure ). Airway organoids … could also be used to discover effective antiviral drugs to …

… As a secondary screen, we examined whether the six compounds identified above exert any
dose-dependent antiviral effects in airway organoids (Figure 2A). Cell viability was found to …

… Human seasonal coronaviruses usually cause mild upper-respiratory tract infection, but …
This study aims to establish human airway organoids (hAOs)-based systems for seasonal …

… in airway organoids (AOs) cultured at air-liquid interface (ALI). Results were similar to the
commercially obtained bronchial … both the upper and the lower airways, with a slight replicative …

… organoids to study respiratory viruses and test therapeutics. … recapitulate aspects of human
airway disease are essential … a versatile airway organoid model, the human nose organoid (…

… and broad‐spectrum antiviral agents ribavirin and favipiravir … of these drugs are still
controversial in the treatment of COVID… the repair of airways and the respiratory epithelium after …

… SARS-CoV-2 infection in the pulmonary tissue are required, along with consistent methods
in the constant search for possible therapeutic agents, effective antiviral drugs, and vaccines. …

… clinical trials of many antivirals, such as … of antivirals, human organoid systems could provide
a more robust environment for pre-clinical testing, which provides detailed insights into drug …

… the viral life cycle and evaluate the drug efficacy of anti-viral drugs is essential. In this study,
… bronchial organoids (hBO) from commercially available cryopreserved human bronchial …