… irreversible airway remodeling of severe asthma. On the contrary, this preventive approach
might reduce the direct and indirect heavy socio-economic consequences of severe asthma …

… airway remodeling (AR) contribute to the symptomatology of the disease. The most severely
ill asthma … key inflammatory cytokines involved in asthma pathogenesis. Although clinical …

… to the remodeling process in severe asthma. Smooth muscle hypertrophy and … airway
vascularity appear to contribute to airway remodeling and physiologic changes in severe asthma (…

… Asthmatic airway remodeling is the pathophysiological modifications of the … Airway remodeling
is partially reversible in mild asthma but mostly irreversible in chronic severe asthma. It is …

… mild asthma or healthy subjects, which correlates with pathologic measures of remodeling
and … MDCT scanning may be a useful technique for assessing airway remodeling in asthma …

… Severe asthma may involve an irreversible obstructive pattern, and structural changes in
bronchial airways … study was to compare airway remodeling in severe asthmatic children with or …

… We sought to characterize subjects with severe asthma with and without chronic persistent
airflow obstruction with respect to airway wall remodeling (histopathologic and radiologic) …

… changes that occur in the airways of subjects with severe asthma, we compared the findings
… of subjects with severe asthma with those of subjects with well-controlled moderate asthma. …

… not observe more pronounced airway remodeling in the severe asthma cohort. Although our
… the airway wall becomes thickened over time in both normal subjects and asthma subjects. …

… populations have been reported in which asthma severity does not correlate with submucosal
… severe asthma through mechanisms that may or may not involve airway remodeling. …