Diesel exhaust enhances airway responsiveness in asthmatic subjects

C Nordenhäll, J Pourazar, MC Ledin… - European respiratory …, 2001 - Eur Respiratory Soc
… inflammation characterized by an increase in airway eosinophils, … airway responsiveness,
but did not induce any inflammatory changes 24, 26. The increase in airway responsiveness

Diesel exhaust particles enhance airway responsiveness following allergen exposure in mice

H Takano, T Ichinose, Y Miyabara… - …, 1998 - Taylor & Francis
… that DEP enhanced also airway responsiveness to inhaled … of airways accompanied by
airway hyperresponsiveness (9). … enhanced eosinophilic airway inflammation and airway

Anti-oxidant N-acetylcysteine diminishes diesel exhaust-induced increased airway responsiveness in person with airway hyper-reactivity

C Carlsten, MJ MacNutt, Z Zhang, F Sava… - Toxicological …, 2014 - academic.oup.com
airway responsiveness and anti… airway responsiveness due to DE are attenuated by
thiol anti-oxidant supplementation, particularly in those with underlying airway hyper-responsiveness

Diesel exhaust inhalation enhances airway hyperresponsiveness in mice

Y Miyabara, T Ichinose, H Takano… - International archives of …, 1998 - karger.com
airway responsiveness and to analyze bronchoalveolar lavage (BAL), respectively. After
measurement of airway responsiveness, lungs were removed for determinations of histology. …

Diesel exhaust enhances allergic airway inflammation and hyperresponsiveness in mice

Y Miyabara, H Takano, T Ichinose, HB Lim… - American journal of …, 1998 - atsjournals.org
… Therefore, we exposed mice to DE and sensitized them with OVA, then analyzed airway
inflammation, airway responsiveness, the production of antigen-specific IgE and IgG 1 , and the …

Airway inflammatory responses to diesel exhaust in allergic rhinitics

N Larsson, J Brown, N Stenfors, S Wilson… - Inhalation …, 2013 - Taylor & Francis
… In subjects with allergic asthma, controlled DE exposure has elicited increased bronchial
hyper-responsiveness, without any evidence of an augmented neutrophilic or allergic airway

Effect of diesel exhaust particles on allergic reactions and airway responsiveness in ovalbumin-sensitized brown Norway rats

CC Dong, XJ Yin, JYC Ma, L Millecchia… - Toxicological …, 2005 - academic.oup.com
diesel exhaust particles (DEP) prior to ovalbumin (OVA) sensitization in rats reduced OVA-induced
airwayAirway responsiveness was examined on day 30, and animals were sacrificed …

Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel

N Stenfors, C Nordenhäll, SS Salvi… - European …, 2004 - Eur Respiratory Soc
… the airways, with asthmatic subjects thought to be especially sensitive. The authors
hypothesised that exposure to diesel exhaust (DE), a major source of PM, would induce airway

[HTML][HTML] Mechanistic link between diesel exhaust particles and respiratory reflexes

RK Robinson, MA Birrell, JJ Adcock, MA Wortley… - Journal of Allergy and …, 2018 - Elsevier
… We demonstrate a direct interaction between DEP and airway C-fiber afferents. In anesthetized
guinea pigs intratracheal administration of DEPs activated airway C-fibers. The organic …

How does diesel exhaust impact asthma?

JR Balmes - Thorax, 2011 - thorax.bmj.com
airway inflammation and hyper-responsiveness. … airway injury from diesel exhaust occurs
to trigger activation of inflammatory signalling cascades. Alternatively, the persistent airway