… Manipulating T cell responses by targeting the PI3K/Akt/mTOR … functions by targeting
downstream mTOR, an important … Targeting different levels of the PI3K/Akt/mTOR signalling …

… of PI3K/Akt/mTOR signaling in cancer and summarizing efforts for developing PI3K/Akt/mTOR
inhibitors as either mono-therapy or combination therapy in different cancer settings. We …

… )-Akt and the mammalian target of rapamycin (mTOR) … -Akt-mTOR signaling pathway in
different cancer conditions and the importance of natural products targeting the PI3K-Akt-mTOR …

… temsirolimus, exemplify targeted inhibition of PI3K/AKT/mTOR in the clinic and many others
are … /AKT/mTOR signaling from the perspective of novel molecular targets for cancer therapy …

… segmental overgrowth syndromes of the PI3K/AKT/mTOR signaling pathway provide the
basis for developing targeted therapeutic strategies. This holds promise for treating progressive …

… /Akt/mTOR pathway. In this review we will give an overview of the PI3K/Akt/mTOR pathway
… We will then outline how the targeting of this pathway may lead to novel treatment strategies …

… PI3K/Akt/mTOR pathway has emerged as a potential therapeutic … the association of
PI3K/Akt/mTOR signalling in colon cancer and … in colon cancer and its therapeutic strategies. …

… Aurora-A triggers the AKT/mTOR pathway in endometrial cancer, which stimulates cell …
AKT/mTOR inhibitor in combination with chemotherapy intervention may be a therapeutic strategy …

… , therapeutic strategies for PTX-resistant GC are uninvestigated. Thus, we attempted to
identify potential molecular candidates and to develop therapeutic options for PTX-resistant GC. …

… therapeutics. The tumors and genetic mutations which are targeted for the development of
anticancer therapeutics … for developing anticancer therapeutic strategies. Among these, PI3K …