Evaluation of the aldosterone synthase (CYP11B2) gene polymorphism in patients with myocardial infarction
C Hengstenberg, SR Holmer, B Mayer, H Löwel… - …, 2000 - Am Heart Assoc
… Because increased aldosterone levels may … aldosterone synthase gene polymorphism.
The aim of the present study was therefore to investigate, first, whether the aldosterone synthase …
The aim of the present study was therefore to investigate, first, whether the aldosterone synthase …
Molecular mechanisms of myocardial remodeling. The role of aldosterone
C Delcayre, B Swynghedauw - Journal of molecular and cellular cardiology, 2002 - Elsevier
… To conclude (i) after a myocardial infarction local production of aldosterone and … increases
myocardial aldosterone synthase mRNA concentration, showing that the cardiac aldosterone …
myocardial aldosterone synthase mRNA concentration, showing that the cardiac aldosterone …
Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction
MG Modena, P Aveta, A Menozzi, R Rossi - American heart journal, 2001 - Elsevier
… demonstrated that cardiac fibrosis is mediated by angiotensin II and aldosterone; this …
myocardial infarction. The aim of this study was to evaluate whether the suppression of aldosterone …
myocardial infarction. The aim of this study was to evaluate whether the suppression of aldosterone …
Cardiovascular effects of aldosterone and post–acute myocardial infarction pathophysiology
JN Cohn, W Colucci - The American journal of cardiology, 2006 - Elsevier
… Aldosterone synthase is present in rat heart, 50 and selective activation of the cardiac
aldosterone synthase … increases in aldosterone by almost 4-fold in the myocardium. After AMI, …
aldosterone synthase … increases in aldosterone by almost 4-fold in the myocardium. After AMI, …
Activation of cardiac aldosterone production in rat myocardial infarction: effect of angiotensin II receptor blockade and role in cardiac fibrosis
JS Silvestre, C Heymes, A Oubénaïssa, V Robert… - Circulation, 1999 - Am Heart Assoc
… The existence of a steroidogenic system has also been suggested in cardiac tissue. …
and aldosterone synthesis, 11β-hydroxylase (11β-OHase) and aldosterone synthase (aldo-synthase)…
and aldosterone synthesis, 11β-hydroxylase (11β-OHase) and aldosterone synthase (aldo-synthase)…
Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction
A Hautanen, P Toivanen, M Manttari, L Tenkanen… - Circulation, 1999 - Am Heart Assoc
… in the promoter of the gene encoding aldosterone synthase (CYP11B2) is associated with
… myocardial infarction (MI). We hypothesized that this polymorphism was a risk factor for MI. …
… myocardial infarction (MI). We hypothesized that this polymorphism was a risk factor for MI. …
Persistent cardiac aldosterone synthesis in angiotensin II type 1A receptor–knockout mice after myocardial infarction
J Katada, T Meguro, H Saito, A Ohashi, T Anzai… - Circulation, 2005 - Am Heart Assoc
… Ang II–independent synthesis of cardiac aldosterone in post-… Ang II–independent aldosterone
synthesis is induced in the … roles of cardiac aldosterone synthesis in post-MI remodeling. …
synthesis is induced in the … roles of cardiac aldosterone synthesis in post-MI remodeling. …
Central infusion of aldosterone synthase inhibitor attenuates left ventricular dysfunction and remodelling in rats after myocardial infarction
BS Huang, RA White, M Ahmad, J Tan… - Cardiovascular …, 2009 - academic.oup.com
… of the aldosterone synthase inhibitor FAD286 12 on changes in: (i) aldosterone and corticosterone
… and dysfunction by echocardiography and Millar catheter; and (iii) cardiac histology. …
… and dysfunction by echocardiography and Millar catheter; and (iii) cardiac histology. …
[HTML][HTML] Cardiac aldosterone production and ventricular remodeling
C Delcayre, JS Silvestre, A Garnier, A Oubenaissa… - Kidney international, 2000 - Elsevier
… myocardial infarction (MI) on the cardiac steroidogenic system, it was observed that
aldosterone-synthase mRNA and the aldosterone … activation of myocardial aldosterone synthesis. …
aldosterone-synthase mRNA and the aldosterone … activation of myocardial aldosterone synthesis. …
Analysis of promoter region polymorphism in the aldosterone synthase gene (CYP11B2) as a risk factor for myocardial infarction
S Patel, R Steeds, K Channer… - American journal of …, 2000 - academic.oup.com
… gene (CYP11B2), which may influence plasma aldosterone levels, has … any association with
risk of myocardial infarction (MI). … We conclude that the aldosterone synthase −344 promoter …
risk of myocardial infarction (MI). … We conclude that the aldosterone synthase −344 promoter …
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