… mechanisms of resistance to EGFR or ALK inhibitors in EGFR/ALK co-altered NSCLC. To …
in a cohort of EGFR mutation, ALK rearrangement and EGFR/ALK co-altered patients. The …

… Importantly, some of these genetic events (such as EGFR mutations and ALK translocations)
are targetable with currently available molecular agents, while for others intensive …

… Besides ALK and KRAS alterations, several mutations in various … with EGFR mutations.
Rarely occurrence of other driver genes mutations were reported associated to EGFR mutations, …

… of EGFR, KRAS, BRAF, ALK and MET genetic alterations and … cases harbouring an EGFR
mutation and an amplification of … In summary, in our series, EGFR mutations were significantly …

… mutations were found in this ADC subtype (table 1). Of all analysed molecular alterations, only
EGFR mutation … predominant ADCs showing higher EGFR mutation rates (table 1), mainly …

… EGFR mutation and ALK translocation is rare, and one case with two genetic alterations
showed differential sensitivities to EGFR and ALK … both EGFR mutation and ALK translocation in …

… that concomitant EGFR mutations and ALK … EGFR mutation in exon 21 (L858R) and ALK
rearrangement in naive and relapsed tumors. Tumor cells seem to harbor both gene alterations …

… of EGFR mutations in women and never smoking NSCLC patients, it has been suggested
that 57% of all EGFR mutations … the frequency of molecular alterations in EGFR, ALK, HER2, …

… (EGFR) mutation and anaplastic lymphoma kinase (ALK) … having concomitant EGFR and
ALK alterations have been … concomitant EGFR and ALK alterations using mutation detection …

… Interestingly, 5.6% of all EGFR mutations in our study were observed in squamous cell
carcinomas and the remaining in adenocarcinomas. A recent review reported the frequency of …