Potential allergenicity response to structural modification of irradiated bovine α-lactalbumin

X Meng, X Li, X Wang, J Gao, H Yang, H Chen - Food & function, 2016 - pubs.rsc.org
… bovine α-La at doses of 1–10 kGy. We then examined the structural changes in the irradiated
α-… We also evaluated the potential allergenicity of the irradiated α-La by determining the IgG/…

Reducing the allergenicity of α-lactalbumin after lipid peroxidation

L Lv, K He, F Sun, X Lin, L Ye, Y Lyu, L Liu… - Journal of Agricultural …, 2021 - ACS Publications
This study analyzed the effect of lipid peroxidation using 2,2′-azobis(2-amidinopropane)dihydrochloride
(AAPH) and acrolein on the in vitro and in vivo allergenicity of α-lactalbumin (α-…

Structural analysis and allergenicity assessment of an enzymatically cross-linked bovine α-lactalbumin polymer

X Li, H Bai, Y Wu, W Cheng, Y Wu, Z Wu, A Yang… - Food & function, 2020 - pubs.rsc.org
α-lactalbumin was cross-linked by polyphenol oxidase from Agaricus bisporus and the changes
in the structure, digestibility and allergenicity of α-lactalbumin … -linked α-lactalbumin was …

Characterization of the potential allergenicity of irradiated bovine α-lactalbumin in a BALB/c mouse model

X Meng, X Li, J Gao, H Chen - Food and Chemical Toxicology, 2016 - Elsevier
… Obviously, the support for the allergenicity assessment of the iALA provided by the study
is insufficient. Accordingly, this work aims to further evaluate the allergenicity of iALA (10 kGy-…

[HTML][HTML] Structure and allergenicity of α-lactalbumin: effects of ultrasonic prior to glycation and subsequent phosphorylation

W Chen, Q Chen, H Zhou, Y Shao, Y Wang… - Food Science and …, 2023 - Elsevier
α-lactalbumin (BLA) induced severe cow's milk allergy. In … was proposed to reduce BLA
allergenicity. Result showed that … Minimum allergenicity was detected during BLA treatment after …

Visualization of clustered IgE epitopes on α-lactalbumin

H Hochwallner, U Schulmeister, I Swoboda… - Journal of Allergy and …, 2010 - Elsevier
… When tested with sera from 4 patients with allergy to α-La, we found that rα-La inhibited the
… and allergenic activity to CM, rα-La, and α-La–derived peptides for patients with CM allergy

IgE and IgG binding epitopes on α-lactalbumin and β-lactoglobulin in cow's milk allergy

KM Järvinen, P Chatchatee, L Bardina… - … archives of allergy and …, 2001 - karger.com
… of food allergy in the first years of life. We recently defined IgE and IgG binding epitopes for α
s1 -… recognition of certain epitopes and clinical symptoms of cow’s milk allergy (CMA). Since …

The mechanism of the reduction in allergenic reactivity of bovine α-lactalbumin induced by glycation, phosphorylation and acetylation

J Liu, W Chen, Y Shao, J Zhang, Z Tu - Food chemistry, 2020 - Elsevier
… Bovine α-lactalbumin (α-Lac) allergy is a common health problem. This study assesses
the allergenic reactivity and the structural properties of α-Lac after protein modification (glycation, …

Isolation and allergenicity evaluation of glycated α-lactalbumin digestive products and identification of allergenic peptides

X Wang, Z Tu, Y Ye, G Liu, Y Hu, H Wang - Food Chemistry, 2022 - Elsevier
… the allergenicity of glycated α-lactalbumin (ALA) digestive products and identify its allergenic
… The allergenicity of the three fractions of glycated ALA was lower than that in ALA-D, …

Bioactivity of β-lactoglobulin and α-lactalbumin—Technological implications for processing

DEW Chatterton, G Smithers, P Roupas… - International Dairy …, 2006 - Elsevier
… Consequently, there is no consensus between studies regarding the allergenicity of α-la.
The lack of agreement between studies might be related firstly to the thermal history of the …