Thymic stromal lymphopoietin: master switch for allergic inflammation

YJ Liu - The Journal of experimental medicine, 2006 - rupress.org
… underlying TSLP-induced allergic inflammation. Thymic stromal lymphopoietin (TSLP) is a
novel IL-7–like cytokine, originally cloned from a murine thymic stromal cell line, that supports …

Thymic stromal lymphopoietin and allergic disease

SF Ziegler - Journal of Allergy and Clinical Immunology, 2012 - Elsevier
… in driving allergic inflammatory responses. One such product is thymic stromal lymphopoietin
(… TSLP in the development and progression of allergic diseases. This review will highlight …

Role of thymic stromal lymphopoietin in allergy and beyond

R Ebina-Shibuya, WJ Leonard - Nature Reviews Immunology, 2023 - nature.com
… In the context of tissue injury, macrophage-derived progranulin induces TSLP production
by mouse airway epithelial cells, leading to allergic inflammation 28,29 . In addition, the cross-…

The role of thymic stromal lymphopoietin (TSLP) in allergic disorders

SF Ziegler - Current opinion in immunology, 2010 - Elsevier
… in driving allergic inflammatory responses. One such product is thymic stromal lymphopoietin
(TSLP)… this work and place TSLP in the inflammatory cascade that leads to allergic disease. …

The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond

F Roan, BD Bell, TA Stoklasek… - Journal of leukocyte …, 2012 - academic.oup.com
… During allergic inflammation, the primary producers of TSLP are epithelial cells, keratinocytes,
and stromal cells, although recent data have demonstrated that DCs and mast cells are …

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

B Zhou, MR Comeau, TD Smedt, HD Liggitt… - Nature …, 2005 - nature.com
… To investigate further the involvement of TSLP signaling in allergic inflammation, we sensitized
and intranasally challenged groups of Tslpr −/− , Tslpr +/− and Tslpr +/+ mice with OVA. …

Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation

CK Wong, S Hu, PFY Cheung… - American journal of …, 2010 - atsjournals.org
allergic inflammation through the activation of dendritic cells and mast cells for initiating
inflammatory … /keratinocyte–eosinophil–mediated allergic inflammation, we examined the …

Thymic stromal lymphopoietin

R He, RS Geha - Annals of the New York Academy of Sciences, 2010 - Wiley Online Library
… induce a Th2 response in our model of allergic skin inflammation induced by EC sensitization.
It is … , to initiate an innate phase of allergic inflammatory response, or to aggravate allergic

Thymic stromal lymphopoietin (TSLP) is associated with allergic rhinitis in children with asthma

S Bunyavanich, E Melen, JB Wilk, M Granada… - … and molecular allergy, 2011 - Springer
… of TSLP and its ability to drive Th2 dominant inflammation. Second, a limited number of in …
and murine studies, and supports our understanding of TSLP driving allergic inflammation. …

Human thymic stromal lymphopoietin: a novel epithelial cell-derived cytokine and a potential key player in the induction of allergic inflammation

V Soumelis, YJ Liu - Springer seminars in immunopathology, 2004 - Springer
… Dendritic cells (DCs) play an important role in several models of allergy, but … stromal
lymphopoietin (TSLP), a novel IL-7-like cytokine, might represent an early trigger of the allergic