Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU. 1

J Liu, X Jiang, K Liu, J Deng, Y Qiu, W Wei… - Immunologic …, 2024 - Springer
… for the diagnosis and management of allergic and non-allergic rhinitis set by the British
Society for Allergy and Clinical Immunology [28]. Patients who met one of these criteria: (…

Allergen immunotherapy enhances the immunosuppressive effects of Treg cells to alleviate allergic rhinitis by decreasing PU-1+ Treg cell numbers

YL Qiao, WE Jiao, S Xu, YG Kong, YQ Deng… - International …, 2022 - Elsevier
… can reduce the proportion of PU-1+ Treg cells in AR patients, which enhances the
immunosuppressive effects of Treg cells in alleviating allergic rhinitis. PU-1+ Treg cells numbers can …

[PDF][PDF] High frequency of T helper type 9 cells in Chinese patients with allergic rhinitis

XQ Wang, GH Hu, HY Kang, Y Shen, X Ke… - Asian Pac J Allergy …, 2015 - apjai-journal.org
… has a synergistic effect with PU.1 to promote Th9 … PU.1 into Th9 and Th2 cultures leads to
both an increased production of IL-9, and a decrease in Th2 cell production, resulting in a PU.1

[PDF][PDF] Anti-interleukin-9 antibody increases the effect of allergen-specific immunotherapy in murine allergic rhinitis

JH Shin, DH Kim, BY Kim, SW Kim… - Allergy, asthma & …, 2017 - synapse.koreamed.org
… population of CD4+ T cells, develop airway neutrophilia via production of IL-17 in allergic
airways.We evaluated the effect of anti-IL-9 antibody on both the mRNA expression of PU.1 (a …

Profiles of IgE sensitization to dust mite allergen components in patients with allergic rhinitis and asthma

X Wang, X Pu, L Chen, M Guo, C Zheng… - … er bi yan hou tou Jing …, 2022 - europepmc.org
… Objective:To study the differences and clinical significance of dust mite allergen components
in allergic rhinitis(AR) and allergic rhinitis with asthma syndrome(ARAS) patients. Methods:…

Expression levels of transcription factor PU. 1 and interleukin‐9 in atopic dermatitis and their relation to disease severity and eruption types

AM Hamza, SS Omar… - International Journal …, 2017 - Wiley Online Library
… development of allergic asthma and allergic rhinitis, while its role in AD is still to be
investigated. This study aimed to measure gene expression levels of interleukin-9 (IL-9) and PU.1, …

Application of proteomics in allergic rhinitis

X Pu, X Wang, Y Chen, H Wang, J Yin - Lin Chuang er bi yan hou …, 2022 - europepmc.org
… The prevalence of allergic rhinitis(AR)is increasing year by … on clinical manifestations and
allergen detection, but there is … the diagnosis and treatment of allergic rhinitis, which provides a …

The effect of treatment with fexofenadine and fluticasone propionate on the gene expression levels of Th9 transcription factors in patients with allergic rhinitis

A asghar Askari, P Feizollahi, A Rezaiemanesh… - Heliyon, 2021 - cell.com
… In this study, we assessed the expression levels of IRF4, BATF, and PU.1 genes in the
peripheral blood cells of AR patients before and after one month of treatment with fexofenadine …

Serum metabolomics study of patients with allergic rhinitis

…, T Wang, J Wang, Z Ma, S Pu - Biomedical …, 2020 - Wiley Online Library
Allergic rhinitis (AR) negatively affects the healthy lives of many individuals. Most previous
1 INTRODUCTION Allergic rhinitis (AR) is one of the most common diseases reported …

[HTML][HTML] Neutralization of interleukin-9 ameliorates symptoms of allergic rhinitis by reducing Th2, Th9, and Th17 responses and increasing the Treg response in a …

ZW Gu, YX Wang, ZW Cao - Oncotarget, 2017 - ncbi.nlm.nih.gov
PU.1 and IRF4 are key proteins that contribute to the Th9 phenotype and are essential …
The mRNA levels of PU.1 and Irf4 (encoding Th9 cell transcription factors) and the mRNA/protein …