[HTML][HTML] Allopregnanolone decreases evoked dopamine release differently in rats by sex and estrous stage

APS Dornellas, GC Macedo, MH McFarland… - Frontiers in …, 2021 - frontiersin.org
… is inhibitory due to its allosteric actions at GABA A receptors, and based on the above
evidence that drugs that enhance GABA A receptor activity reduce dopamine release, we …

The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens

F Rougé‐Pont, W Mayo, M Marinelli… - European Journal of …, 2002 - Wiley Online Library
… the activity of the mesencephalic dopaminergic (DA) projection … measuring extracellular
concentrations of dopamine (DA) in … AlloP dose-dependently increased the release of DA in the …

Effect of centrally injected allopregnanolone on sexual receptivity, luteinizing hormone release, hypothalamic dopamine turnover, and release in female rats

MR Laconi, RJ Cabrera - Endocrine, 2002 - Springer
… Turnover Rate in MBH and POA Allopregnanolone increased dopamine and dihydroxy…
In the MBH, allopregnanolone increased dopamine (p < 0.001) but showed a decrease in …

Changes in stress-stimulated allopregnanolone levels induced by neonatal estradiol treatment are associated with enhanced dopamine release in adult female rats …

P Porcu, V Lallai, A Locci, S Catzeddu, V Serra… - …, 2017 - Springer
… EB treatment enhances stress-stimulated allopregnanolone levels and dopamine output in
adult … The persistent decrease in brain allopregnanolone concentrations, induced by neonatal …

Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output

L Dazzi, M Serra, G Vacca, S Ladu, A Latrofa… - Brain research, 2002 - Elsevier
… finasteride enhanced both maximal increase of dopamine and … These results suggest that
endogenous allopregnanolone … with potentiation of dopamine release induced by stress or by …

Multifunctional aspects of allopregnanolone in stress and related disorders

A Bali, AS Jaggi - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
… , the levels of allopregnanolone are increased to normalize … develop against increased
allopregnanolone levels probably due … may result in variable release pattern of allopregnanolone. …

Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation

LJ Mosher, R Cadeddu, S Yen, JL Staudinger… - …, 2019 - Elsevier
… is modulated by the activation of dopamine receptors. Using rodent models, we previously
reported that gating deficits caused by dopamine receptor activation - as measured by the …

Allopregnanolone modulates striatal dopamingergic activity of rats under different gonadal hormones conditions

MR Laconi, PC Reggiani, A Penissi, R Yunes… - Neurological …, 2007 - Taylor & Francis
… During estrus, amphetamineinduced striatal dopamine (DA) release is enhanced relative
to other days of the estrus cycle3,4. There is also estrous cycle-dependent variation in striatal …

Allopregnanolone: An overview on its synthesis and effects

S Diviccaro, L Cioffi, E Falvo, S Giatti… - Journal of …, 2022 - Wiley Online Library
… by peripheral nerve injury, the levels of ALLO are increased in the spinal cord, together with
dopamine release from cortical dopaminergic neurones, 192 and prevents the dopamine

Allopregnanolone in mood disorders: Mechanism and therapeutic development

S Chen, L Gao, X Li, Y Ye - Pharmacological Research, 2021 - Elsevier
… GABA is an inhibitory neurotransmitter, which is released from … ALLO reduces basal dopamine
level in the PFC and nucleus … of either ALLO or KSS improved anxious-like behaviors and …