Down-regulation of alpha-2u globulin in renal mitochondria of STZ-induced diabetic rats observed by a proteomic method

SH Sun, SQ Liu, CP Cai, R Cai, L Chen… - Annales d' …, 2012 - Elsevier
Methods.–Mitochondrial proteins extracted from renal … expression were identified as alpha-2u
globulin (mature protein, … Our results suggest that down-regulation of alpha-2u globulin …

Differentiation of protein species of alpha-2u-globulin according to database entries: A half-theoretical approach

S Aksu, F Tanrikulu - Journal of Proteomics, 2016 - Elsevier
… The alpha-2u-globulin protein, the main subject of this study, is the most abundant protein in
adult male rat urine. In this investigation there are 19 spots identified as alpha-2u-… alpha-2u-…

Proteomic identification of a large complement of rat urinary proteins

V Thongboonkerd, JB Klein, JM Arthur - Nephron Experimental …, 2003 - karger.com
… Six proteins [membrane metallo-endopeptidase, solute carrier family 3, meprin 1 alpha, …
immunoblot methods [14, 15], we performed 2-D Western blot analyses to confirm proteomic

Stage-specific quantitative changes in renal and urinary proteome during the progression and development of streptozotocin-induced diabetic nephropathy in rats

V Sharma, K Tikoo - Molecular and cellular biochemistry, 2014 - Springer
… B appeared in the urinary proteome at the fourth week of … of major urinary protein (alpha
2u globulin) in the urine as … Various methods for comparing urinary proteome have been …

Identification of a Transducin (beta)-like 3 protein as a potential biomarker of prediabetes from rat urine using proteomics

HR Mofokeng - 2010 - etd.uwc.ac.za
… 16 Mass spectrum of the trypsin digested C8 with the alpha-2u … a method for the enrichment
of low abundance and low molecular weight proteins. • To generate 2D urine proteome

Proteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome?

L Smith, O Qutob, MB Watson, AW Beavis, D Potts… - Neoplasia, 2009 - Elsevier
… subunit alpha type 2 (PSMA2) and proteasome subunit alpha … and used a global 2DE-MS
proteomic approach to reveal an up-… a range of complementary proteomic methods to analyze …

[HTML][HTML] Differential expression of proteins in renal cortex and medulla: a proteomic approach

JM Arthur, V Thongboonkerd, JA Scherzer, J Cai… - Kidney international, 2002 - Elsevier
… For instance alpha 2u globulin binds pheromones in rat urine and allows for their release
during drying 13 . Calbindin is a vitamin D-dependent calcium binding protein that is found …

Ten years of proteomics in multiple sclerosis

AS Farias, F Pradella, A Schmitt, LMB Santos… - …, 2014 - Wiley Online Library
… central methodology of the study (Fig. 1A). 2DE has been the basis of proteomics since its
beginning, but for large-scale proteomic … replaced by shotgun proteomics techniques. These …

Proteome studies on liver tissue in a phenobarbital-induced rat model

Q Wu, YH Zhang, X Zhao, WL Shi, XP Pu - European journal of …, 2011 - Elsevier
… We used such a sensitive method to avoid any errors caused by time differences. … study,
alpha-2u globulin precursor is highly expressed in the phenobarbital-induced model. Alpha 2u-…

Combined Proteomic Analysis of Liver Tissue and Serum in Chronically Alcohol‐Fed Rats

M Yamada, M Satoh, M Seimiya… - Alcoholism: Clinical …, 2013 - Wiley Online Library
… We used the agarose 2-DE method to examine proteomic changes in rat liver homogenates
and cytosol fractions and the 3-step method to evaluate proteomic changes in serum …