Alpha and beta thalassemia

HL Muncie Jr, JS Campbell - American family physician, 2009 - aafp.org
Alpha thalassemia is the result of deficient or absent synthesis of alpha globin chains, leading
to excess beta globin chains. Alpha globin chain production is controlled by two genes on …

[HTML][HTML] Differences in spectra of alpha and beta chains of hemoglobin between isolated state and in tetramer.

Y Sugita - Journal of Biological Chemistry, 1975 - Elsevier
… that of the isolated alpha and beta chains, and the difference … spectral change in alpha
chains and that beta chains show a … to the spectral changes in beta chains. Difference spectra of …

Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide.

PA Moss, RJ Moots, WM Rosenberg… - Proceedings of the …, 1991 - National Acad Sciences
… V alpha and V beta sequences seen on these T cells is remarkably conserved as are certain
junctional sequences associated with alpha and beta chains… TCR V alpha and V beta genes …

The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence.

JA Lopez, DW Chung, K Fujikawa… - Proceedings of the …, 1988 - National Acad Sciences
… The leucine-rich sequence in the beta chain of GPIb is flanked on both sides by amino …
alpha chain of GPIb and leucine-rich alpha 2-glycoprotein. The amino-terminal region of the beta

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation.

R König, X Shen, RN Germain - The Journal of experimental medicine, 1995 - rupress.org
… This site is in the alpha 2 domain, positioned in single class II heterodimers in such a way
that it cannot simultaneously interact with the same CD4 molecule as the beta 2 site. The …

Both alpha and beta chains of HLA‐DC class II histocompatibility antigens display extensive polymorphism in their amino‐terminal domains.

L Schenning, D Larhammar, P Bill, K Wiman… - The EMBO …, 1984 - embopress.org
… of the DC chains may be a reflection of a function distinct from that of the DR chains. Apart
from … here the complete sequences of two cDNA clones encoding HLA-DC antigen chains. …

Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S

P Garcia de Frutos, RI Alim, Y Hardig, B Zoller… - 1994 - ashpublications.org
… differential regulation of C4BP alpha- and beta-chain expression, and the concentration of
free protein S to be the resulting molar excess of protein S over C4BP beta+. This mechanism …

Structural requirements for pairing of alpha and beta chains in HLA-DR and HLA-DP molecules.

DR Karp, CL Teletski, D Jaraquemada… - The Journal of …, 1990 - rupress.org
… DP beta chain sequences were constructed. Expression of these chimeric beta chains with
DR and DP alpha chains … Both alpha chains paired with beta chains in which only the beta 1 …

The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides.

JS Danska, AM Livingstone, V Paragas… - The Journal of …, 1990 - rupress.org
… of the MHC alpha helices, whereas V/J alpha and V/D/J beta … sequences in both TCR alpha
and beta chains, and differences in … TCR alpha chains without foreknowledge of the V alpha

Neurons express hemoglobin α‐and βchains in rat and human brains

F Richter, BH Meurers, C Zhu… - Journal of …, 2009 - Wiley Online Library
Hemoglobin is the oxygen carrier in vertebrate blood erythrocytes. Here we report that
hemoglobin chains are expressed in mammalian brain neurons and are regulated by a …