[HTML][HTML] Value of αfetoprotein as an early biomarker for treatment response to sorafenib therapy in advanced hepatocellular carcinoma

AI Plano Sánchez, L Velasco Roces… - Oncology …, 2018 - spandidos-publications.com
… best response (15,16). Thus, it is important to perform studies that assess possible biomarkers
or measures of response, to allow us to determine probable response predictors (17). …

Association of postoperative biomarker response with recurrence and survival in patients with hepatocellular carcinoma and high alpha-fetoprotein expressions (> 400 …

L Liang, MD Wang, YM Zhang, WG Zhang… - Journal of …, 2021 - Taylor & Francis
… predictive value of postoperative AFP response on long-term … definition for postoperative
complete response of serum AFP, … complete and incomplete biomarker response of serum AFP …

Alpha fetoprotein is more than a hepatocellular cancer biomarker: from spontaneous immune response in cancer patients to the development of an AFP-based cancer …

R Bei, GJ Mizejewski - Current Molecular Medicine, 2011 - ingentaconnect.com
… T cell responses to HLA-A*0201-restricted peptides derived from human alpha fetoprotein.
J … Hierarchy of alpha fetoprotein (AFP)-specific T cell responses in subjects with AFP-positive …

[PDF][PDF] Alpha-fetoprotein as a potential surrogate biomarker for atezolizumab+ bevacizumab treatment of hepatocellular carcinoma

AX Zhu, F Dayyani, CJ Yen, Z Ren, Y Bai, Z Meng… - Clinical Cancer …, 2022 - AACR
Alpha-fetoprotein as a potential surrogate biomarker for atezolizumab + bevacizumab …
displayed potential as surrogate biomarkers of response to this combination. Results 467 …

[HTML][HTML] Alpha-fetoprotein: Past, present, and future

YH Yeo, YT Lee, HR Tseng, Y Zhu, S You… - Hepatology …, 2024 - journals.lww.com
biomarker for monitoring the treatment response of HCC. In addition to its role as a biomarker,
… We also review its utility as an HCC biomarker in combination with other biomarkers and …

Biology and significance of alphafetoprotein in hepatocellular carcinoma

PR Galle, F Foerster, M Kudo, SL Chan… - Liver …, 2019 - Wiley Online Library
biomarkers are being used or studied to improve outcomes. The most commonly used
biomarker for HCC is serum alpha-fetoprotein (… prognosis and monitoring response to treatment. …

Alpha-fetoprotein is a biomarker of unfolded protein response and altered proteostasis in hepatocellular carcinoma cells exposed to sorafenib

A Houessinon, A Gicquel, F Bochereau, C Louandre… - Cancer letters, 2016 - Elsevier
Sorafenib is the treatment of reference for advanced hepatocellular carcinoma (HCC). A
decrease in the serum levels of Alpha-fetoprotein (AFP) is reported to be the biological …

[HTML][HTML] Alpha-fetoprotein response predicts treatment outcomes in patients with unresectable hepatocellular carcinoma receiving immune checkpoint inhibitors with …

WF Hsu, HW Wang, CK Chen, HC Lai… - American Journal of …, 2021 - ncbi.nlm.nih.gov
… AFP response was a predictor of disease control, PFS, and OS. These findings indicate
that AFP response can serve as a biomarker to predict treatment outcomes in patients with …

[HTML][HTML] Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials

R Montal, C Andreu-Oller, L Bassaganyas… - British journal of …, 2019 - nature.com
… The clinical utility of serum alpha-fetoprotein (AFP) in patients with hepatocellular … an
accepted prognostic cut-off and a predictor of response to ramucirumab. Those AFP-high tumours (…

[HTML][HTML] Association between early response of alpha-fetoprotein and treatment efficacy of systemic therapy for advanced hepatocellular carcinoma: A multicenter …

G Hou, B Liu, ZQ Fan, C Li, JP Zhang, YH Guo… - Frontiers in …, 2023 - frontiersin.org
Frontiers | Association between early response of alpha-fetoprotein and treatment efficacy
of systemic therapy for advanced hepatocellular carcinoma: A multicenter cohort study from …