Biology and significance of alphafetoprotein in hepatocellular carcinoma

PR Galle, F Foerster, M Kudo, SL Chan… - Liver …, 2019 - Wiley Online Library
… In fact, numerous biomarkers have been studied in HCC, but alphafetoprotein (AFP) remains
the most widely used and accepted serum marker since its discovery over 60 years ago. …

… accuracy of des-gamma-carboxy prothrombin and alpha-fetoprotein alone or in combination for hepatocellular carcinoma: A systematic review and meta-analysis

J Fan, Y Chen, D Zhang, J Yao, Z Zhao, Y Jiang, Y Li… - Surgical Oncology, 2020 - Elsevier
… Most recommendations of clinical guidelines were the same as the conclusions of this
meta-analysis [17], but some studies suggested that DCP could diagnosis early-stage …

[HTML][HTML] Highlights for α-fetoprotein in determining prognosis and treatment monitoring for hepatocellular carcinoma

XS Xu, K Qu, C Liu, YL Zhang, J Liu… - World journal of …, 2012 - ncbi.nlm.nih.gov
… , we found that this study was the main source of the heteregeneity in this meta-analysis,
and after the exclusion of this study, the HR estimate decreased to 0.40 (95%CI, 0.33-0.49), as …

Alpha-fetoprotein for diagnosis, prognosis, and transplant selection

F Trevisani, F Garuti, A Neri - Seminars in Liver Disease, 2019 - thieme-connect.com
Alpha-fetoprotein was first identified in human fetal sera by Bergstrand and Czar in 1956,
and its use as a tumor marker for HCC was first proposed in the 1960s. Alpha-fetoprotein is a …

Congenital Deficiency versus Hereditary Persistence of Human Alpha-fetoprotein: A Meta-analysis and Overview of Potential Biomedical Consequences

G Mizejewski - Journal of Pediatric Sciences, 2012 - dergipark.org.tr
… Raised alphafetoprotein in maternal serum with anencephalic pregnancy. Lancet. 1973; 2: …
Immature teratoma producing alphafetoprotein without components of yolk sac tumor in the …

[HTML][HTML] Update on the applications and limitations of alpha-fetoprotein for hepatocellular carcinoma

H Hanif, MJ Ali, AT Susheela, IW Khan… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Alpha-fetoprotein (AFP) is an oncofetal glycoprotein that has been used as a tumor marker
for hepatocellular carcinoma (HCC) in combination with ultrasound and other imaging …

[HTML][HTML] Alpha-fetoprotein: Past, present, and future

YH Yeo, YT Lee, HR Tseng, Y Zhu, S You… - Hepatology …, 2024 - journals.lww.com
Alpha-fetoprotein (AFP) is a glycoprotein that plays an important role in immune regulation
with critical involvement in early human development and maintaining the immune balance …

Elevated alpha-fetoprotein: differential diagnosis-hepatocellular carcinoma and other disorders

RJ Wong, A Ahmed, RG Gish - Clinics in liver disease, 2015 - liver.theclinics.com
… Surveillance with alpha-fetoprotein (AFP) in combination with abdominal ultrasonography
every 6 … for HCC and their use in conjunction with serum alpha-fetoprotein (AFP) is reviewed. …

Test characteristics of α-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C: a systematic review and critical analysis

S Gupta, S Bent, J Kohlwes - Annals of internal medicine, 2003 - acpjournals.org
Background: Patients with hepatitis C virus (HCV) are at increased risk for hepatocellular
carcinoma. Although serum α-fetoprotein (AFP) is often used to detect hepatocellular …

Accuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: a systematic review

A Colli, M Fraquelli, G Casazza… - Official journal of the …, 2006 - journals.lww.com
… Summary receiver operating characteristic (SROC) curve for the detection of HCC by
alpha-fetoprotein. The figures near circles indicate the cutoff values used in the different studies. …