Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin

AJ Saunders, L Bertram, K Mullin… - … molecular genetics, 2003 - academic.oup.com
… Based on the biological and genetic data … polymorphisms in A2M for genetic association
with AD (Table 1). Family-based association studies have been largely supportive of genetic

A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha

AG Wilson, C Gordon, FS di Giovine… - European journal of …, 1994 - Wiley Online Library
… The TNF polymorphism that we describe lies within the promoter region of the … The
polymorphism screened in this study is the only one characterized so far in the human TNF-a gene. …

TNF-α gene polymorphisms and expression

RR El-Tahan, AM Ghoneim, N El-Mashad - Springerplus, 2016 - Springer
… Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine with an important role in
… A significant genetic association between TNF-α promoter −308A/G polymorphism and SLE …

Systematic review by meta-analyses on the possible role of TNF-α polymorphisms in association with Alzheimer's disease

D Di Bona, G Candore, C Franceschi, F Licastro… - Brain research …, 2009 - Elsevier
association of the common polymorphisms comprehensively defining the genetic variability
of the TNF-α gene … control genetic association studies. Available data suggested a significant …

Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?

BM Brinkman, TW Huizinga, SS Kurban… - British journal of …, 1997 - academic.oup.com
… The association between the -238 polymorphism and … No associations between the
TNF-alpha -308, +70 and -376 … Our data indicate that the TNF-alpha -238GA genotype is …

A comprehensive review of genetic association studies

JN Hirschhorn, K Lohmueller, E Byrne… - Genetics in …, 2002 - nature.com
… We identified 268 genes that contain polymorphisms reported to be associated with 1 of 133
… encoding tumor necrosis factor alpha, have been associated with 20 different diseases or …

Association between− G308A tumor necrosis factor alpha gene polymorphism and schizophrenia

F Boin, R Zanardini, R Pioli, CA Altamura, M Maes… - Molecular …, 2001 - nature.com
genetic susceptibility to schizophrenia. We studied the distribution of −G308A TNFα gene
polymorphism … This biallelic base exchange polymorphism directly affects TNFα plasma levels. …

Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women

SCE Schuit, FH de Jong, L Stolk… - European journal of …, 2005 - academic.oup.com
… There are limitations to genetic association studies. First, they can be influenced by
population stratification or heterogeneity. This is especially true for case-control studies in a …

Multiple alpha‐synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population

R Myhre, M Toft, J Kachergus… - Acta Neurologica …, 2008 - Wiley Online Library
… This demonstrates that genetic association studies in regions of high LD often provide limited
information about the physical location of the variant causing the association. In addition, it …

Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta, and IL-1Ra genes.

JT Cvetkovic, S Wallberg-Jonsson, B Stegmayr… - The Journal of …, 2002 - jrheum.org
genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha
polymorphism. … A tumour necrosis factor alpha polymorphism is not associated with rheumatoid …