… , put forward by Poser in 1986, four elements are required in order to develop MS: 1) genetic
susceptibility, 2) an environmental and probably viral immune-mediated event, 3) alteration …

… in multiple sclerosis (MS) are present from its early stages, an intensive scientific interest has
been directed to biomarkers of neuro-axonal damage in body fluids … and cerebrospinal fluid …

… to multiple sclerosis compared … multiple sclerosis could be distinguished from those patients
who will remain as clinically isolated syndrome by proteomic analysis of cerebrospinal fluid …

… multiple sclerosis (MS) has evolved alongside the characterization of cytokines and chemokines
in cerebrospinal fluid … and chemokines in different body fluids in people with MS (pwMS) …

… pressure hydrocephalus and multiple sclerosis. These … cerebrospinal fluid volume and velocity
of cerebrospinal fluid … hydrocephalus: cerebral ischemia or altered venous hemodynamics…

… Flow cytometry demonstrated reduced cerebrospinal fluid (… , but may reflect an altered humoral
immune system rather … Serial measurements of serum and cerebrospinal fluid (CSF) Abs …

… Therefore, we here employed state-of-the-art quantitative proteomics techniques to differentiate
between cerebrospinal fluid (CSF) samples of multiple sclerosis patients before and after …

… concentration of essential metal elements in the CNS could alter the clinical course of patients.
We have … of progressive MS is via the alteration of cytokine production. This proceeds by …

… CSF dynamics may be altered by pathologies such as hydrocephalus, Chiari malformation,
… of CSF space anatomy and cerebrospinal fluid dynamics physiology – prerequisites for …

… alter cerebrospinal venous flow, if that is hypothesized to be the underlying pathology
leading to the development of MS. It is also well known that genetic predisposition alone cannot …