Reduced spinal cord parenchymal cerebrospinal fluid circulation in experimental autoimmune encephalomyelitis

AP Fournier, M Gauberti, A Quenault… - Journal of Cerebral …, 2019 - journals.sagepub.com
… An alteration of parenchymal cerebrospinal fluid circulation (CSF) has been proposed to …
multiple sclerosis, we show a reduction of parenchymal CSF circulation specifically in the spinal

Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid

J Mellergård, M Edström, M Vrethem… - Multiple Sclerosis …, 2010 - journals.sagepub.com
… therapeutic effects in patients with multiple sclerosis (MS). … systemically and intrathecally in
multiple sclerosis. We used … , CCL22) in blood and cerebrospinal fluid (CSF) from 31 patients …

Glymphatic system impairment in multiple sclerosis: relation with brain damage and disability

A Carotenuto, L Cacciaguerra, E Pagani, P Preziosa… - Brain, 2022 - academic.oup.com
… , cerebrospinal fluid crosses the perivascular space entering the interstitium and moving
toward perivenous spaces. While moving, fluid … CSF circulation alteration mirrors the temporal …

Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients

M Jacobsen, S Cepok, E Quak, M Happel, R Gaber… - Brain, 2002 - academic.oup.com
… of multiple sclerosis patients, suggesting a role for these CD8 + T cells in the pathogenesis
of multiple sclerosis. … ‐associated antigens and disease pathogenesis in multiple sclerosis. …

[HTML][HTML] Quantifying cerebrospinal fluid dynamics: a review of human neuroimaging contributions to CSF physiology and neurodegenerative disease

NH Mehta, RA Suss, JP Dyke, ND Theise… - Neurobiology of …, 2022 - Elsevier
Cerebrospinal fluid (CSF), predominantly produced in the … CSF volume and flow dynamics
regulate intracranial pressure … CSF fluid dynamics and better relate CSF volume and flow to …

Serum and cerebrospinal fluid levels of soluble adhesion molecules in multiple sclerosis: predominant intrathecal release of vascular cell adhesion molecule-1

AG Droogan, SA McMillan, JP Douglas… - Journal of …, 1996 - Elsevier
… We wished to determine if there is a specifk alteration in circulating adhesion mok~ule
levels in clinically active multiple sclerosis and whether or *ot the response is pmdominaody …

Cerebrospinal fluid lipocalin 2 in patients with clinically isolated syndromes and early multiple sclerosis

M Khalil, A Renner, C Langkammer… - Multiple Sclerosis …, 2016 - journals.sagepub.com
… We demonstrate altered LCN2 regulation in early MS and provide first evidence for this to
be possibly linked to both clinical MS activity and iron accumulation in the basal ganglia. …

Anomalous venous blood flow and iron deposition in multiple sclerosis

AV Singh, P Zamboni - Journal of Cerebral Blood Flow & …, 2009 - journals.sagepub.com
… magnetic resonance imaging techniques, support the hypothesis that iron deposits in MS
are a consequence of altered cerebral venous return and chronic insufficient venous drainage. …

… stabilization and effective B-lymphocyte depletion in the cerebrospinal fluid and peripheral blood of a patient with fulminant relapsing-remitting multiple sclerosis

O Stüve, S Cepok, B Elias, A Saleh… - Archives of …, 2005 - jamanetwork.com
… A limited effect of rituximab on B lymphocytes in the cerebrospinal fluid compartment of
patients with primary progressive multiple sclerosis (MS) was recently reported. …

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

L Piccio, C Buonsanti, M Cella, I Tassi, RE Schmidt… - Brain, 2008 - academic.oup.com
… Furthermore, TREM-2 was detected on a subset of CSF monocytes by flow cytometry, and
multiple sclerosis subjects. The elevated levels of sTREM-2 in CSF of multiple sclerosis