Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn
NM Martinez, KW Lynch - Immunological reviews, 2013 - Wiley Online Library
… regulated at the level of splicing in immune cells and to determine … been shown to regulate
alternative splicing in human T cells … of alternative splicing in the adaptive immune system and …
alternative splicing in human T cells … of alternative splicing in the adaptive immune system and …
Alternative splicing of pre-mRNA in the control of immune activity
Z Su, D Huang - Genes, 2021 - mdpi.com
… the generation of immune-associated alternative splice variants, clinical … immune responses
to the neoantigens produced by alternative splicing, and finally, we issue some alternative …
to the neoantigens produced by alternative splicing, and finally, we issue some alternative …
Alternative splicing in cancer and immune cells
… For the moment, little is known about the potential action of this alternative isoform in the
immune response. Nevertheless, it is known that this isoform including exon 5 is more …
immune response. Nevertheless, it is known that this isoform including exon 5 is more …
Impacts and mechanisms of alternative mRNA splicing in cancer metabolism, immune response, and therapeutics
Q Peng, Y Zhou, L Oyang, N Wu, Y Tang, M Su, X Luo… - Molecular Therapy, 2022 - cell.com
… in regulating cancer metabolism and immune response. We discussed how alternative
splicing regulates metabolic reprogramming of cancer cells and antitumor immune response, and …
splicing regulates metabolic reprogramming of cancer cells and antitumor immune response, and …
Consequences of regulated pre-mRNA splicing in the immune system
KW Lynch - Nature Reviews Immunology, 2004 - nature.com
… The role of alternative splicing in the control of immune responses is just one more layer of
regulation that we must understand to fully appreciate this highly evolved and crucial system. …
regulation that we must understand to fully appreciate this highly evolved and crucial system. …
The role of alternative splicing in the control of immune homeostasis and cellular differentiation
… system is composed of T and B lymphocytes and they are able to generate specific immune
responses to defined antigens, and can generate immunological memory. B cell lineage …
responses to defined antigens, and can generate immunological memory. B cell lineage …
Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo
H Nishimura, T Yajima, Y Naiki, H Tsunobuchi… - The Journal of …, 2000 - rupress.org
… alternative splicing at the 5′ upstream of exon 5 in mice. To elucidate the potential roles of
IL-15 isoforms in immune responses … IL-15 cDNA with an alternative exon 5 (alternative IL-15 …
IL-15 isoforms in immune responses … IL-15 cDNA with an alternative exon 5 (alternative IL-15 …
Alternative splicing as a key player in the fine‐tuning of the immunity response in Arabidopsis
J Kufel, N Diachenko, A Golisz - Molecular plant pathology, 2022 - Wiley Online Library
… of the splicing machinery, have been established. Modulation of gene expression in response
to stress includes alternative splicing, … How these processes affect plant immunity is mostly …
to stress includes alternative splicing, … How these processes affect plant immunity is mostly …
Global analysis of alternative splicing during T-cell activation
JY Ip, A Tong, Q Pan, JD Topp, BJ Blencowe… - Rna, 2007 - rnajournal.cshlp.org
… The role of alternative splicing (AS) in eliciting immune responses is poorly understood. We
used quantitative AS microarray profiling to survey changes in AS during activation of Jurkat …
used quantitative AS microarray profiling to survey changes in AS during activation of Jurkat …
Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells
Y Tu, X Wu, F Yu, J Dang, J Wang, Y Wei, Z Cai… - BMC immunology, 2019 - Springer
… Our findings indicated that TTP may regulate the immune response via the regulation of
alternative splicing and potentially transcription, which greatly expands the current …
alternative splicing and potentially transcription, which greatly expands the current …
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