Lung fibrosis and fibrosis in the lungs: is it all about myofibroblasts?
E Ortiz-Zapater, J Signes-Costa, P Montero, I Roger - Biomedicines, 2022 - mdpi.com
… lung, pulmonary capillary endothelial cells, through EndoMT, may serve as a source of
fibroblasts in pulmonary fibrosis … Apart from this difference in AMs and IMs, lung macrophage …
fibroblasts in pulmonary fibrosis … Apart from this difference in AMs and IMs, lung macrophage …
Silica‐induced pulmonary fibrosis involves the reaction of particles with interstitial rather than alveolar macrophages
DH Bowden, C Hedgecock… - The Journal of …, 1989 - Wiley Online Library
… of interstitial macrophages by silica induces a greater fibrotic response than a macro… Alveolar
macrophages lavaged from fibrotic lungs after silica have been shown to secrete fibroblast …
macrophages lavaged from fibrotic lungs after silica have been shown to secrete fibroblast …
Hypoxia-inducible factor-1α mediates TGF-β-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis
M Ueno, T Maeno, M Nomura… - … of Physiology-Lung …, 2011 - journals.physiology.org
… alveolar macrophages, myofibroblasts, and fibroblasts in lung biopsies obtained from idiopathic
pulmonary fibrosis … rodent bleomycin (BLM)-induced pulmonary fibrosis models (5, 25, 26…
pulmonary fibrosis … rodent bleomycin (BLM)-induced pulmonary fibrosis models (5, 25, 26…
Cytokines and pulmonary fibrosis
K Zhang, SH Phan - Neurosignals, 2004 - karger.com
… actin gene expression, alteration of the contractile phenotype of fibroblasts and regu lation
of diverse functions of lung inflammatory and epithelial cells which can further impact on the …
of diverse functions of lung inflammatory and epithelial cells which can further impact on the …
[HTML][HTML] Nitrated fatty acids reverse pulmonary fibrosis by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages
… of pulmonary fibrosis, we hypothesized that it might elicit the PPARγ down-regulation seen in
IPF fibroblasts… responses to TGFβ in cultured human lung fibroblasts. Exposure to TGFβ up-…
IPF fibroblasts… responses to TGFβ in cultured human lung fibroblasts. Exposure to TGFβ up-…
M2 macrophages have unique transcriptomes but conditioned media does not promote profibrotic responses in lung fibroblasts or alveolar epithelial cells in vitro
EM Hult, SJ Gurczynski… - … of Physiology-Lung …, 2021 - journals.physiology.org
… Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing interstitial lung disease of unknown
… it used polarized BMDMs rather than lung macrophages or moAMs that may have different …
… it used polarized BMDMs rather than lung macrophages or moAMs that may have different …
Pathobiology of pulmonary fibrosis
E Crouch - American Journal of Physiology-Lung Cellular …, 1990 - journals.physiology.org
… Intravascular coagulation, and the elaboration of procoagulant activities by alveolar
macrophages, fibroblasts, and epithelial cells could also contribute to the release of important …
macrophages, fibroblasts, and epithelial cells could also contribute to the release of important …
Stimulation of rat and murine alveolar macrophage proliferation by lung fibroblasts.
BE Lehnert, YE Valdez, NM Lehnert… - American journal of …, 1994 - atsjournals.org
… Hallmark features of pulmonary fibrosis that occur during chronic inflammation are
excessive accumulations of fibroblasts and collagen in the intraluminal and interstitial compartments …
excessive accumulations of fibroblasts and collagen in the intraluminal and interstitial compartments …
Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts
… injury syndromes: interrelationship between the alveolar macrophage and the septal
fibroblast. Int J Radiat Oncol Biol Phys 1992; 24:93-101; PMID:1512168; http://dx.doi.org/10.1016/…
fibroblast. Int J Radiat Oncol Biol Phys 1992; 24:93-101; PMID:1512168; http://dx.doi.org/10.1016/…
Angiotensin-TGF-β1 crosstalk in human idiopathic pulmonary fibrosis: autocrine mechanisms in myofibroblasts and macrophages
… -rich primary cultures of lung fibroblasts from patients with IPF (HIPF isolates), primary … the
lung fibrotic process. Although the relative role of alveolar macrophages in lung fibrosis has …
lung fibrotic process. Although the relative role of alveolar macrophages in lung fibrosis has …