Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

C Morse, T Tabib, J Sembrat… - European …, 2019 - Eur Respiratory Soc
macrophages ameliorates bleomycin-induced lung fibrosis [… alveolar macrophages drive
bleomycin-induced lung fibrosis … were between SPP1 macrophages and fibroblasts, suggesting …

[HTML][HTML] Alveolar cells under mechanical stressed niche: critical contributors to pulmonary fibrosis

J Yang, X Pan, L Wang, G Yu - Molecular Medicine, 2020 - Springer
… the pathogenesis of pulmonary fibrosis from a previously … cells, fibroblasts, macrophages,
mast cells and alveolar stem cells … -talk between alveolar macrophages and the rigid alveolar

New mechanisms of pulmonary fibrosis

RM Strieter, B Mehrad - Chest, 2009 - Elsevier
lung fibroblasts and myofibroblasts play an important role in ECM deposition in pulmonary
fibrosis, … There is one classic theory and two contemporary theories for the origin of fibroblasts/…

Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis

F Zhang, EA Ayaub, B Wang… - EMBO molecular …, 2020 - embopress.org
… -54) is shown to alleviate pulmonary fibrosis with no detectable … macrophages, suppressing
the consequent fibroblast … reprogram fibrotic lung macrophages to a more anti-fibrotic state in …

Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

MA Gibbons, AC MacKinnon… - American journal of …, 2011 - atsjournals.org
… and lung macrophages during pulmonary fibrosis, and emphasize the importance of the
alternatively activated … A vicious circle of alveolar macrophages and fibroblasts perpetuates …

… , morphology, and tumor necrosis factor-alpha secretion of alveolar macrophage subpopulations during the development of bleomycin-induced pulmonary fibrosis.

MP Everson, DB Chandler - The American journal of pathology, 1992 - ncbi.nlm.nih.gov
… Clark JG, Greenberg J: Modulation of the effects of alveolar macrophages on lung fibroblast
… RP: Human alveolar macrophage inhibition of lung fibroblast growth. A prostaglandin-…

Inhibition of bleomycin-induced pulmonary fibrosis by nordihydroguaiaretic acid. The role of alveolar macrophage activation and mediator production.

SH Phan, SL Kunkel - The American journal of pathology, 1986 - ncbi.nlm.nih.gov
… level of lung collagen metabolism, lung macrophage activationand … pulmonary fibrosis and
that such inhibition is associated with inhibition of lung macrophage activation and fibroblast

Growth differentiation factor 15 facilitates lung fibrosis by activating macrophages and fibroblasts

Y Takenouchi, K Kitakaze, K Tsuboi… - Experimental cell research, 2020 - Elsevier
… are known to be involved in pulmonary fibrosis. However, the effect of … alveolar epithelial
cells involves the acquisition of the profibrotic phenotypes by lung macrophages and fibroblasts

Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor …

Y Kapanci, A Desmouliere, JC Pache… - American journal of …, 1995 - atsjournals.org
… of a-SM actin by alveolar myofibroblasts Our study suggests the … fibrotic areas the alveolar
surface was lined by type II epithelial cells; these cells as well as the alveolar macrophages

Cellular players in lung fibrosis

A N. Lekkerkerker, J Aarbiou, T van Es… - Current …, 2012 - benthamdirect.com
… , alveolar macrophages are thought to produce the majority of the active TGFβ that promotes
pulmonary fibrosis [… A vicious circle of alveolar macrophages and fibroblasts perpetuates …