… Generation of human airway and alveolar organoids from hESCs. (A) Schematic of … stages
from hESCs to human airway organoids (hAWOs) and human alveolar organoids (hALOs). (B) …

… on establishing alveolar organoids from endogenous lung … well as the use of alveolar
organoids for the study of respiratory … organoids that allows airway differentiation but not alveolar …

… in long-term expandable organoids and generated mature airway and alveolar … increased
viral titer in alveolar organoids, indicating the lower susceptibility of alveolar epithelial cells to …

… tip progenitor cells which in vivo differentiate into both airway and alveolar cells. We grew
these lung bud tip organoids (LBT) from canalicular stage human fetal lungs 16–17 pcw (post‐…

… This review focuses on alveolar organoids and approaches to lung … lung’s airways,
bronchoalveolar, and alveolar regions. Organoids have been utilized effectively in modeling human …

… This organoid can comprise airway and/or alveolar epithelial cells, depending on the
characteristics of the stem/progenitor cells and the culture conditions, such as the medium …

… , who showed that modulation of growth factor signaling in these cultures leads to the
generation of distal (alveolar-like) or proximal (airway-like) organoids that are epithelial only, …

… To determine which factors in SN medium are most important for promoting airway versus
alveolar fate of the late-stage tips, freshly isolated tips from 17 to 21 pcw lungs were directly …

… airway organoids from a variety of human BAL samples and show that these organoids contain
diverse airway … of BAL-derived alveolar organoids. These techniques significantly expand …

… and alveolar epithelial cells (Chiu et al., 2022). Here, we provide … alveolar organoids from
long-term expanding human lung organoids, the same source for generating airway organoids …