… and alveolar epithelial cells (Chiu et al., 2022). Here, we provide … alveolar organoids from
long-term expanding human lung organoids, the same source for generating airway organoids …

… , the cells form alveolar-like organoids expressing mature AEC … lipoprotein signaling in 3D
organoids. Our approach yields … derived from airway cells, few human alveolar epithelial cell (…

… Here, we used human airway and alveolar organoids to characterize the shedding, fitness,
… We report that Omicron efficiently replicates in the human airway, but not in the alveoli, and …

… displays remarkable plasticity, and in a limited and surprising fashion recapitulates
aspects of both proximal airway and distal alveolar cell self-assembly and differentiation. …

… cells could generate human AT2 cells, we generated organoids from these cells … organoids
grew extensively and immunostaining showed that more than 60% of the resultant organoids …

… studies in human alveolar and airway epithelial cells [15]. An example of the use of human
lung … Lung epithelial organoids have been derived from airway basal cells [29] and from …

… Recently, organoids representative of the respiratory system have been generated from …
The hPSC-derived alveolar spheroids reported in this study are similar in structure and …

… However, these cells were no longer present in our culture after the first passage and there
was no contamination with airway epithelial cells in the alveolar organoid cultures after the …

… into both small airway (CCSP + ) and alveolar (SPC + ) … our alveolar organoids for evidence
of alveolar type 1 (AT1) cells… cell markers, in alveolar organoids. No significant difference …

… The human respiratory system, consisting of the airway and alveoli, is one of the most …
Therefore, in recent years, to mimic the complexity of the lung, airway and alveoli organoid …