… of influenza viruses in humans. Based on the long-term expanding 3D human airway organoids,
we developed … No type I and type II alveolar epithelial cells were present. Thus, these …

… alveolar organoids consisting of human pluripotent stem cell-derived alveolar epithelial cells
and primary human … Instead, most studies have used airway epithelial cells because of the …

… human airway organoids for a toxicological assessment of TWPs, and our findings revealed
that human airway organoids … As for lung organoids, the 3D organoid model of alveolar type …

… (chronic bronchitis), airway wall thickening and/or destruction of the alveoli with airspace …
Next, we assessed the ability of LMSCs to support the formation of organoids, where alveolar …

… Our results indicate that iPSC-derived airway and alveolar … Directed differentiation of human
iPSCs to alveolar or airway … thawed and expanded in 3D organoid culture and are simple …

… perfused lungs and precision cut lung slices), two-dimensional in vitro cell-line (A549,
BEAS-2B, Calu-3) and three-dimensional in vitro ALI (gold-standard and co-culture) and organoid …

… developed an in vitro model using human airway and alveolar organoids to infect each
virus. They identified difference in the replication capacity of the two viruses and the degree of …

… their proliferative and differentiation potential, these airway organoids (AOs) can be … airway
organoids emerge from this protocol; it also remains to be determined why alveolar organoids …

… Here, we established human distal lung organoids (hDLO) from distal lung parenchymal …
organoid in our culture is a mixture of multiple cell types, including alveolar cells and airway …

… mutant fibrotic organoids. IL-11 was detected predominantly in type 2 alveolar epithelial …
Finally, IL-11 induced fibrosis in WT organoids, while its deletion prevented fibrosis in HPS4 …