… ” or “alveolar organoid”. We screened articles focused on alveolar organoid cultures and
their … Another study used hESCs-derived airway and alveolar lung organoids to show that …

… organoids when supplemented with appropriate growth factors, which resemble lung tissue
in morphology and function. They form the bronchial and alveolar … form alveolar or bronchial …

… been hampered by limited access to human alveolar tissue and the differences between
mice and humans. Thus, the development of human alveolar organoid (AO) models that mimic …

… organoids were to the native human fetal lung airway epithelium, we generated single-cell
data for in vitro-derived airway or basal cell organoids … differentiate into alveolar cells. No bud …

… employed to generate lung organoids. Yet, the derivation of airway organoids and their
subsequent … Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid …

… , showed branching airway and early alveolar structures resembling those present in lungs
… human gestation. We show here that the treatment of such organoids with a lung and airway …

… human organoids that can be derived from peripheral blood and differentiated towards airway
and alveolar … to develop an alveolar organoid model from primary human AT2 cells 47 , 48 …

… The airways conduct airflow to the distal alveoli in which gas exchange between the
exterior and the underlying vasculature takes place. Clearance of microbes and suspended …

… The proximalized epithelial airway organoids generated in this chapter can also be differentiated
to ciliated cells using pharmacologic inhibition of Notch signaling or can be expanded …

… recapitulate aspects of human airway disease are essential for … a versatile airway organoid
model, the human nose organoid (… of human alveolar type II-like cells. EMBO J 40:e105912. …